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This text is the written form of the proceedings of a satellite symposium associated with the 1988-meeting of the Society for Neu roscience. The symposium was held 12 November 1988 in the auditor ium of the Addictions Research Foundation, Toronto, Canada. The ac tual writing took place across the months following the symposium. The symposium was sponsored by the Addictions Research Foundation, Toronto, Canada, the National Institute on Alcohol Abuse and Alcoholism, U. S. A. , and Rensselaer, Troy, NY, U. S. A. Du Pont Pharmaceuticals provided some financial assistance. Contributors also received specific support for their own projects and these are ac knowledged at the end of each chapter. T...
Addiction focuses on the emergence, nature, and persistence of addictive behavior, as well as the efforts of addicts to overcome their condition. Do addicts act of their own free will, or are they driven by forces beyond their control? Do structured treatment programs offer more hope for recovery? What causes relapses to occur? Recent scholarship has focused attention on the voluntary aspects of addiction, particularly the role played by choice. Addiction draws upon this new research and the investigations of economists, psychiatrists, philosophers, neuropharmacologists, historians, and sociologists to offer an important new approach to our understanding of addictive behavior. The notion tha...
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First multi-year cumulation covers six years: 1965-70.
There is now enough basic work to sketch out the principal systems at all levels of the brain, from prefrontal cortex to lower brainstem, which are orchestrated to provide control of food selection, preference and consumption. At the same time, the complex interplay between central systems and signals generated from peripheral systems include the gut, liver and fat stores, as well as the interactions with the neuroendocrine system can be described in some detail. A continuing theme throughout the book is that the functional analysis of appetite and food intake cannot be limited to a single focus, e.g. hypothalamic neuropeptides and their interactions, but must be based on a fully integrated ...