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The Principles of Clinical Cytogenetics
In this thoroughly revised and expanded third edition of the highly praised classic, The Principles of Clinical Cytogenetics, a panel of hands-on experts update their descriptions of the basic concepts and interpretations involved in chromosome analysis to include the many advances that have occurred in the field. Among the highlights are a full chapter devoted to advances in chromosome microarray, soon to become a standard of care in this field, as well as an update on chromosome nomenclature as reflected in ISCN 2009. Other features include an update on automation to reflect the current state of the art, an update on hematopoietic neoplasms to reflect the new WHO guidelines, and updates on all regulatory changes that have been implemented. Cutting edge and readily accessible, The Principles of Clinical Cytogenetics, Third Edition offers physicians who depend on the cytogenetics laboratory for the diagnosis of their patients, students in cytogenetics programs, graduate and medical students studying for board examinations, cytogenetics technologists, and cytogeneticists a clear understanding of what happens in the cytogenetics laboratory to facilitate accurate and timely diagnoses.
The Principles of Clinical Cytogenetics
Enlightening and accessible, The Principles of Clinical Cytogenetics constitutes an indispensable reference for today's physicians who depend on the cytogenetics laboratory for the diagnosis of their patients.
Iscn 2020
This reprint of 'Cytogenetic and Genome Research' contains contributions discussing the subject in-depth. 'Cytogenetic and Genome Research' is a well-respected, international peer-reviewed journal in genetics.
The AGT Cytogenetics Laboratory Manual
Cytogenetics is the study of chromosome morphology, structure, pathology, function, and behavior. The field has evolved to embrace molecular cytogenetic changes, now termed cytogenomics. Cytogeneticists utilize an assortment of procedures to investigate the full complement of chromosomes and/or a targeted region within a specific chromosome in metaphase or interphase. Tools include routine analysis of G-banded chromosomes, specialized stains that address specific chromosomal structures, and molecular probes, such as fluorescence in situ hybridization (FISH) and chromosome microarray analysis, which employ a variety of methods to highlight a region as small as a single, specific genetic seque...
A Pattern of Violence
A law professor and former prosecutor reveals how inconsistent ideas about violence, enshrined in law, are at the root of the problems that plague our entire criminal justice system—from mass incarceration to police brutality. We take for granted that some crimes are violent and others aren’t. But how do we decide what counts as a violent act? David Alan Sklansky argues that legal notions about violence—its definition, causes, and moral significance—are functions of political choices, not eternal truths. And these choices are central to failures of our criminal justice system. The common distinction between violent and nonviolent acts, for example, played virtually no role in crimina...
The Listeners
TheyÕve been listening for longer than you think. A new history reveals howÑand why. Wiretapping is nearly as old as electronic communications. Telegraph operators intercepted enemy messages during the Civil War. Law enforcement agencies were listening to private telephone calls as early as 1895. Communications firms have assisted government eavesdropping programs since the early twentieth centuryÑand they have spied on their own customers too. Such breaches of privacy once provoked outrage, but today most Americans have resigned themselves to constant electronic monitoring. How did we get from there to here? In The Listeners, Brian Hochman shows how the wiretap evolved from a specialized...
Your Easy Way to Chromosomes
These days, hardly a week goes by in the media, without mention of a remarkable advancement in the field of genetics. Cytogenetics is a branch of genetics that is concerned with the study of the structure and function of the chromosomes and their role in heredity. Every individual inherits a pair of chromosomes from each of his parents. Each cell in our body has 46 chromosomes each. Chromosomes carry genetic information in the form of genes. The genes within the chromosomes have a powerful impact on our health, either directly through chromosomal or single gene disorders or by influencing our susceptibility to disease. Cytogenetic study is performed in order to diagnose certain genetic disor...
ABNORMAL KARYOTYPES
In my first book (Your Easy Way To Chromosomes), I talked mainly about the human chromosomes, their structures, abnormality, their syndromes, and chromosomes analysis. In this book I focused on how chromosomal abnormalities happened and showing some of abnormal karyotypes images for each chromosome . A karyotype is a picture of all the chromosomes from an individual’s cells (blood, hair, or any other tissue), photographing them through a microscope and arranging them in pairs, ordered by size and position of centromere. Karyotype test (alternative names Chromosomes Analysis) plays a role in diagnosis genetic diseases which related to chromosomal abnormalities, some birth defects, and even ...
Colorectal Cancer
The contents of Colorectal Cancer: Methods and Protocols aim to instruct investigators in all the key genetic, cellular, and molecular biological methods of analyzing colorectal tumors. The focused techniques and assays are described in sufficient detail to allow researchers to start an experiment on colon tumors and proceed from beginning to end as if the expert in the field who has performed these studies were guiding them at the bench. Of note, most of the chapters in this volume are written by those scientists who p- neered these methods and assays in their respective fields. The chapters in Colorectal Cancer: Methods and Protocols describe “state of the art” methods to analyze color...
