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NMR as a Structural Tool for Macromolecules
The contemplation of truth and beauty is the proper object for which we were created, which calls forth the most intense desires of the soul, and of which it never tires -Hazlitt In his Nobel lecture Purcell commented that when he saw snow in New England after the discovery of NMR, it appeared like "heaps of protons quietly precessing in earth's magnetic field. " If he were to make the comment in the context of how NMR is being used today, he could have conjured up an image of hydrogen, carbon, and nitrogen nuclei in proteins of an earthbound 8rganism subtly orchestrating a quiet symphony of frequencies, from 150 Hz to 2 kHz, carrying clues to the three-dimensional structure of the macromole...
NMR Primer
"This book has one aim: to explain the key two-dimensional protein NMR experiment, the 1H,15N-HSQC, along with variants and extensions, in a generally accessible manner. Vector diagrams of one-, two- and three-dimensional pulse sequences are provided, along with accompanying animated versions. The animations allow the evolution of net magnetisation during the course of the experiments to be visualised and directly compared with the corresponding spin operator terms. First, a brief introduction to spins, populations, the NMR experiment and relaxation is provided. Evolution due to J-coupling is next described and used to explain magnetisation transfer in the HSQC experiment and several variants. The extraction of structural, sequential and dynamic information is then illustrated via various extensions of the HSQC. Extensive footnotes and appendices introduce several more advanced concepts, such as sensitivity enhancement and the TROSY effect."--Publisher's description.
Understanding Quantum Science
Students are naturally drawn to quantum science by the intriguing behaviors of small particles. However, they can also be intimidated by the lengthy and complicated treatment found in the classroom. Understanding Quantum Science: A Concise Primer for Students of Chemistry, Biochemistry, and Physics is a highly accessible book that offers students an opportunity to grasp the most fascinating of quantum topics, without the intimidation. To be sure, math is necessary, but it is introduced as needed and kept concise. The emphasis is on the science: a certain differential equation can be solved, and when it is, we find the energies that hydrogen atom electrons are allowed to have. Each concept is...
Spirit and Nature
Jansenism, the view of the world as dark and fallen, enjoyed its heyday in 17th century Europe. Radner explores Jansenism and its response to purported miraculous events, exploring the interior logic and its implications for Christian pneumatology.
The Question of God
This invaluable text introduces the six great arguments for the existence of God. It requires no specialist knowledge of philosophy and includes a wealth of primary sources from classic and contemporary texts.
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Blaise Pascal
Blaise Pascal (1623-1662), mathematician, physicist, inventor, and religious thinker was a man at odds with his time. The optimism of the Enlightenment and the belief among philosophers and scientists that the universe was both discoverable and rational made them feel invincible. Reason alone, declared the intellectuals, could discover a God of natural religion that was to replace the God of traditional Christianity. Pascal, on the other hand, was not so confident. In his Pens es, he wrote, "The eternal silence of these infinite spaces fills me with dread." For Pascal, the universe was full of a mystery that went far beyond the powers of reason. Blaise Pascal: Reasons of the Heart, the lates...
Perpetual Euphoria
How happiness became mandatory—and why we should reject the demand to "be happy" Happiness today is not just a possibility or an option but a requirement and a duty. To fail to be happy is to fail utterly. Happiness has become a religion—one whose smiley-faced god looks down in rebuke upon everyone who hasn't yet attained the blessed state of perpetual euphoria. How has a liberating principle of the Enlightenment—the right to pursue happiness—become the unavoidable and burdensome responsibility to be happy? How did we become unhappy about not being happy—and what might we do to escape this predicament? In Perpetual Euphoria, Pascal Bruckner takes up these questions with all his unc...
The Paradox of Love
"The sexual revolution is justly celebrated for the freedoms it brought - birth control, the decriminalization of abortion, the liberalization of divorce, greater equality between the sexes, women's massive entry into the workforce, and more tolerance of homosexuality. ...Bruckner argues that our new freedoms have brought new burdens and rules - without, however, wiping out the old rules, emotions, desies and arrangements: the couple, marriage, jealousy, the demand for fidelity, the war between constancy and inconstancy. It is no wonder that love, sex, and relationships today are so confusing, so difficult, and so paradoxical. Drawing on history, politics, psychology, literature, pop culture...
