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Neurology
Mount Sinai Expert Guides: Neurology provides trainees in neurology with an extremely clinical and accessible handbook covering the major neurologic disorders and symptoms, their diagnosis and clinical management. Perfect as a point-of-care resource on the hospital wards and also as a refresher for board exam preparation, the focus throughout is on providing rapid reference, essential information on each disorder to allow for quick, easy browsing and assimilation of the must-know information. All chapters follow a consistent template including the following features: An opening bottom-line/key points section Classification, pathogenesis and prevention of disorder Evidence-based diagnosis, in...
G Protein Pathways
G Protein Pathways is the first of three volumes examining the nature of heterotrimeric G proteins. The text takes an integrated approach to studying common experimental questions at many different levels related to G proteins. Methods related to G proteins using molecular modeling, systems biology, protein engineering, protein biochemistry, cell biology, and physiology are all accessible in the same volume. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
G Proteins
G Proteins
Receptor Molecular Biology
The volumes in this series include contemporary techniques significant to a particular branch of neuroscience. They are an invaluable aid to the student as well as the experienced researcher not only in developing protocols in neuroscience but in disciplines where research is becoming closely related to neuroscience. Each volume of Methods in Neurosciences contains an index, and each chapter includes references. Dr. Conn became Editor-in-Chief of the series beginning with Volume 15, so each subsequent volume could be guest-edited by an expert in that specific field. This further strengthens the depth of coverage in Methods in Neurosciences for students and researchers alike. - Cloning - Expression systems - Signal transduction - Structure-function techniques - Antireceptor antibodies - Regulation - 3-D receptor modeling and computational probing
Endocrinology - E-Book
ENDOCRINOLOGY, edited by J. Larry Jameson, MD, PhD and Leslie J. De Groot, MD, has been considered the definitive source in its field for decades. Now this landmark reference has been exhaustively updated to bring you the latest clinical guidance on all aspects of diagnosis and treatment for the full range of endocrine and metabolism disorders, including new information on diabetes, obesity, MEN I and II, disorders of sex determination, and pituitary tumors. Entirely new chapters on Lipodystrophy Syndromes, Lipoprotein Metabolism, and Genetic Disorders of Phosphate Homeostasis keep you well informed on today’s hot topics. You’ll benefit from unique, global perspectives on adult and pedia...
Beyond Zero and One
“Andrew Smart deftly shows why it’s time for us to think deeply about thinking machines before they begin thinking deeply about us.” —Douglas Rushkoff, author, Escaping the Growth Trap,Present Shock, and Program or Be Programmed “Provocative and cool.” —Cory Doctorow “Forget the Turing test—will the supersmart AIs that we hear so much about these days pass the acid test? In this playful, informative, and prescient book, Andrew Smart brings psychedelics into dialogue with neuroscience in order to challenge the whiz-bang computational views of human and machine sentience that dominate the headlines. Giving robots LSD sounds like a joke, but Smart is dead serious in his critiq...
The Dopamine Receptors
Seven years after the cloning of the rat dopamine D receptor, and four 2 years after the cloning of the last mammalian dopamine receptor identified to date, this seems to be an excellent time to put together the present The Dopamine Receptors volume ofthis series, The Receptors. There has been time for considerable characterization of the novel receptor subtypes, and new, exciting lines of research from the molecular to the behavioral levels are taking shape. We asked the contributors to The Dopamine Receptors to follow the superb example set by the previous volumes in this series by writing compre hensive, historical reviews that will comprise an essential resource for nonspe cialists and n...
Peptidases and Neuropeptide Processing
The volumes in this series include contemporary techniques significant to a particular branch of neuroscience. They are an invaluable aid to the student as well as the experienced researcher not only in developing protocols in neuroscience but in disciplines where research is becoming closely related to neuroscience. Each volume of Methods in Neurosciences contains an index, and each chapter includes references. Dr. Conn became Editor-in-Chief of the series beginning with Volume 15, so each subsequent volume could be guest-edited by an expert in that specific field. This further strengthens the depth of coverage in Methods in Neurosciences for students and researchers alike. - Comprehensive protocols included for: Enzymes involved in the activation of bioactive peptidases and proteins - Prohormone/neuropeptide processing pathways - Enzymes involved in peptide metabolism - Posttranslational processing enzymes
Neuroimmunology
The volumes in this series include contemporary techniques significant to a particular branch of neuroscience. They are an invaluable aid to the student as well as the experienced researcher not only in developing protocols in neuroscience but in disciplines where research is becoming closely related to neuroscience. Each volume of Methods in Neurosciences contains an index, and each chapter includes references. Dr. Conn became Editor-in-Chief of the series beginning with Volume 15, so each subsequent volume could be guest-edited by an expert in that specific field. This further strengthens the depth of coverage in Methods in Neurosciences for students and researchers alike.Comprehensive protocols included for the study of: - The brain-immune system - The neuroimmune system: Effects of the brain on the peripheral immune system - Neuroimmune effects from substances of abuse (e.g. cocaine) to hypnosis - Measurement of interferons, cytokines, natural killer cells, and major histocompatibility complex molecules - Immunohistochemistry methods in the brain - Neuropeptides as immunomodulators
Measurement and Manipulation of Intracellular Ions
This practical book provides the detailed methodology and expert guidance required for measuring and manipulating cytosolic ion concentrations. In addition, the strengths, weaknesses, and pitfalls of various techniques are presented. It is an invaluable source for those needing an objective evaluation of current methodologies and for those contemplating setting up such procedures. - A one-source reference for measuring and manipulating intracellular ions and for comparing and evaluating current methodologies - Includes overviews of Optical probes and reagents - Fabrication and use of ion-selective microelectrodes - Use of NMR spectroscopy - Ionophores
