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The Reverse Transcriptase (RT) of Human Immunodeficiency Virus Type 1 (HIV-1) arguably ranks amongst one of the most extensively studied retroviral enzymes. Heterologous expression and purification of HIV-1 RT in the early eighties, approval of the first nucleoside analogue RT inhibitor (NRTI) in 1987, discovery of resistance to RT inhibitors, approval of the first non-nucleoside analogue RT inhibitor (NNRTI) in 1996 and the various crystal structures of RT with and without bound substrate(s) and/or inhibitors represent only a few of the important milestones that describe the a bench-to-bedside success in the continuing effort to combat HIV-1 infection and its consequences. Nucleoside and no...
Genetics and Biotechnology of Bacilli contains the proceedings of the Second International Conference on Genetics and Biotechnology of Bacilli, held at Stanford University in Stanford, California, on July 6-8, 1983. Contributors discuss the progress that has been made concerning the genetics and biotechnology of Bacillus and focus on topics built around the themes of chromosomal organization, secretion, transcription, gene cloning, gene expression, and synthesis of sporulation-associated products. This text is organized into 33 chapters and begins with an overview of bacteriophage lambda biology, with emphasis on lambda insertion, controlled DNA rearrangements, operator-promoter function, an...
The first substantial overview of the British film industry with emphasis on its genres, stars, and socioeconomic context, British National Cinema by Sarah Street is an important title in Routledge's new National Cinemas series. British National Cinema synthesizes years of scholarship on British film while incorporating the author' fresh perspective and research. Street divides the study of British cinema into four sections: the relation between the film industry and government; specific film genres; movie stars; and experimental cinema. In addition, this beautifully illustrated volume includes over thirty stills from every sphere of British cinema. British National Cinema will be of great interest to film students and theorists as well as the general reader interested in the fascinating scope of British film.
Gone with the Wind an inspiration for the American avant-garde? Mickey Mouse a crucial source for the development of cutting-edge intellectual and aesthetic ideas? As Greg Taylor shows in this witty and provocative book, the idea is not so far-fetched. One of the first-ever studies of American film criticism, Artists in the Audience shows that film critics, beginning in the 1940s, turned to the movies as raw material to be molded into a more radical modernism than that offered by any other contemporary artists or thinkers. In doing so, they offered readers a vanguard alternative that reshaped postwar American culture: nonaesthetic mass culture reconceived and refashioned into rich, personally relevant art by the attuned, creative spectator.
Bacillus Molecular Genetics and Biotechnology Applications contains the proceedings of the Third International Conference on the Genetics and Biotechnology of Bacilli, held at Stanford University in Stanford, California on July 15-17, 1985. Contributors discuss the progress that has been made concerning the molecular genetics and biotechnology of Bacillus and cover topics related to transposons and plasmids, secretion, gene cloning, and gene expression. This volume is organized into five sections encompassing 39 chapters and begins with an overview of the origin and the state of molecular genetics, along with some of the contributions microbiology has made to fundamental biology. It then emp...
In September, 1990, a group of 160 scientists from 19 countries and 21 of the United States met at the Red Lion Inn in Rohnert Park, Sonoma County, California. The purpose of this meeting was to share new information from recent research on the Aspartic Proteinases. This book is a compilation of the information transferred in that forum. The Aspartic Proteinases include all those enzymes from the "fourth" class of proteolytic enzymes, the first three being the Serine, Cysteine and Metalloproteinases. Of course, all the scientists in attendance at the Sonoma Aspartic Proteinase Conference would agree that our current level of understanding of the structure and function of the Aspartic Protein...
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