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Yeast as a Tool in Cancer Research
Leland H. Hartwell Director, Fred Hutchinson Cancer Research Center, Nobel Laureate for Medicine, 2001 Yeast has proved to be the most useful single-celled organism for studying the fundamental aspects of cell biology. Resources are now available for yeast that greatly simplify and empower new investigations, like the presence of strains with each gene deleted, each protein tagged and databases on protein–protein interactions, gene regulation, and subcellular protein location. A powerful combination of genetics, cell biology, and biochemistry employed by thousands of yeast researchers has unraveled the complexities of numerous cellular processes from mitosis to secretion and even uncovered...
Journal of the National Cancer Institute
Each issue is packed with extensive news about important cancer related science, policy, politics and people. Plus, there are editorials and reviews by experts in the field, book reviews, and commentary on timely topics.
Molecular Genetics of Drug Resistance
"Molecular Genetics of Drug Resistance" forms a vital and timely review of the genetic processes behind drug resistance. Starting with an overview of the area, each chapter focuses on a particular target with important sections on drug resistance in malaria and in cancer.
Drug Resistance in Oncology
This timely new reference integrates the latest clinical results and laboratory studies on the resistance of specific cancers to chemotherapeutic drugs-covering drug resistance in lung, breast, ovary, and colon cancer as well as hematological malignancies.
Membranes to Molecular Machines
Today's science tells us that our bodies are filled with molecular machinery that orchestrates all sorts of life processes. When we think, microscopic "channels" open and close in our brain cell membranes; when we run, tiny "motors" spin in our muscle cell membranes; and when we see, light operates "molecular switches" in our eyes and nerves. A molecular-mechanical vision of life has become commonplace in both the halls of philosophy and the offices of drug companies, where researchers are developing “proton pump inhibitors” or medicines similar to Prozac. Membranes to Molecular Machines explores just how late twentieth-century science came to think of our cells and bodies this way. This...
Directory of Graduate Research
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
ABC Proteins
ABC Proteins is an in-depth, up-to-date analysis of all that is known about the subject to date. It discusses and compares evolution, biology and mechanism of action of all known ABC proteins, including the first structural studies as well as clinical implications. It will be useful to anyone trying to stay abreast of the latest findings. This book is sure to become a classic and will regularly be updated. Phylogeny and Evoloution of ABC Transporters Fundamental Aspects of the Mechanism of Action of ABC Transporters Prokaryote ABC Transporters Non-Mammalian Transporters Multidrug Transporters ABC Transporters, Physiological Roles and Human Disease Full color throughout
Who's Who of Canadian Women, 1999-2000
Who's Who of Canadian Women is a guide to the most powerfuland innovative women in Canada. Celebrating the talents and achievement of over 3,700 women, Who's Who of Canadian Women includes women from all over Canada, in all fields, including agriculture, academia, law, business, politics, journalism, religion, sports and entertainment. Each biography includes such information as personal data, education, career history, current employment, affiliations, interests and honours. A special comment section reveals personal thoughts, goals, and achievements of the profiled individual. Entries are indexed by employment of affilitation for easy reference. Published every two years, Who's Who of Canadian Women selects its biographees on merit alone. This collection is an essential resource for all those interested in the achievements of Canadian women.
