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Name Reactions
In this fifth edition of Jack Jie Li's seminal "Name Reactions", the author has added twenty-seven new name reactions to reflect the recent advances in organic chemistry. As in previous editions, each reaction is delineated by its detailed step-by-step, electron-pushing mechanism and supplemented with the original and the latest references, especially from review articles. Now with addition of many synthetic applications, this book is not only an indispensable resource for advanced undergraduate and graduate students, but is also a good reference book for all organic chemists in both industry and academia. Unlike other books on name reactions in organic chemistry, Name Reactions, A Collection of Detailed Reaction Mechanisms and Synthetic Applications focuses on the reaction mechanisms. It covers over 320 classical as well as contemporary name reactions.
Encyclopedia of Molecular Pharmacology
An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.
Heat Shock Protein Inhibitors
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging...
Endoscopic Ear Surgery
Endoscopic Ear Surgery: Principles, Indications, and Techniques Increasingly used as an adjunctive tool in the diagnosis and management of ear disease, middle ear endoscopy has the potential to decrease patient morbidity, prevent disease recurrence, and reduce costs. Its capacity to uncover "hidden" anatomy within the small dimensions of the ear has made it essential for functional surgery, allowing surgeons to preserve key anatomic structures such as the cochlea and facial nerve. Now for the first time, the physicians who pioneered this groundbreaking minimally invasive technique review its indications, advantages, disadvantages, and surgical approaches: Written by the foremost leaders in t...
Language in the Media
This book examines the ways in which the media represents language-related issues, but also how the media's use of language is central to the construction of what people think language is, could or ought to be like. The chapters examine issues of identity, gender, youth, citizenship, politics and ideology across a range of media, including television, radio, newspapers, magazines and the internet. The result is a multilingual survey of the construction of language in and by the media that will be essential reading for students and researchers of sociolinguistics or language and communication.
Understanding Complexity
Peter A. Coming Palo Alto, CA November, 2000 This volwne represents a distillation of the plenary sessions at a unique millenniwn year event -a World Congress of the Systems Sciences in conjunction with the 44th annual meeting of the International Society for the Systems Sciences (ISSS). The overall theme of the conference was "Understanding Complexity in the New Millenniwn. " Held at Ryerson Polytechnic University in Toronto, Canada, from July 16-22,2000, the conference included some 350 participants from over 30 countries, many of whom were representatives of the 21 organizations and groups that co-hosted this landmark event. Each of these co-host organizations/groups also presented a segm...
Inventing Luxembourg
The grand duchy of Luxembourg was created after the Napoleonic Wars, but at the time there was no 'nation' that identified with the emergent state. This book analyses how politicians, scholars and artists have initiated and contributed to nation-building processes in Luxembourg since the nineteenth century, processes that – as this book argues – are still ongoing. The focus rests on three types of representations of nationhood: a shared past, a common homeland and a national language. History was written so as to justify the country's political independence. Territorial borders shifted meaning, constantly repositioning the national community. The local dialect – initially considered German variant – was gradually transformed into the 'national language', Luxembourgish.
Diagnostics, Risk Factors, Treatment and Outcomes of Acute Kidney Injury in a New Paradigm
Acute kidney injury (AKI) is a frequent clinical syndrome among hospitalized patients, independently associated with both short- and long-term mortality. Previous investigations attempted to identify effective interventions to prevent AKI or promote kidney function recovery in patients with AKI. Most were unsuccessful. Hence, additional studies are required in the field of AKI research. In this Special Issue, we are making a call to action to stimulate researchers and clinicians to submit their studies on AKI conducted in nephrology, internal medicine, critical care, and other disciplines that will provide additional knowledge and skills in the field of AKI research, ultimately to improve patient outcomes.
