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General Biophysics
General Biophysics, Volume I deals with the theoretical physics underlying biological phenomena and presents some pertinent experimental results. It explores the molecular foundations of biophysics, the thermodynamics of nonequilibrium systems and membrane transport, nerve impulses, and mechanochemical processes. Comprised of five chapters, this volume begins with an overview of molecular biophysics and the concept of molecular recognition, followed by a discussion of the interaction between antibodies and antigens, the primary processes that determine odor reception, and the importance of intercellular interactions in the existence and development of multicellular organisms. The next chapte...
Advanced Statistics with Applications in R
Advanced Statistics with Applications in R fills the gap between several excellent theoretical statistics textbooks and many applied statistics books where teaching reduces to using existing packages. This book looks at what is under the hood. Many statistics issues including the recent crisis with p-value are caused by misunderstanding of statistical concepts due to poor theoretical background of practitioners and applied statisticians. This book is the product of a forty-year experience in teaching of probability and statistics and their applications for solving real-life problems. There are more than 442 examples in the book: basically every probability or statistics concept is illustrate...
The Triumph of Sociobiology
In The Triumph of Sociobiology, John Alcock reviews the controversy that has surrounded evolutionary studies of human social behavior following the 1975 publication of E.O. Wilson's classic, Sociobiology, The New Synthesis. Denounced vehemently as an "ideology" that has justified social evils and inequalities, sociobiology has survived the assault. Twenty-five years after the field was named by Wilson, the approach he championed has successfully demonstrated its value in the study of animal behavior, including the behavior of our own species. Yet, misconceptions remain--to our disadvantage. In this straight-forward, objective approach to the sociobiology debate, noted animal behaviorist John...
Physiologically Based Pharmacokinetic (PBPK) Modeling
Physiologically Based Pharmacokinetic (PBPK) Modeling: Methods and Applications in Toxicology and Risk Assessment presents foundational principles, advanced techniques and applications of PBPK modeling. Contributions from experts in PBPK modeling cover topics such as pharmacokinetic principles, classical physiological models, the application of physiological models for dose-response and risk assessment, the use of in vitro information, and in silico methods. With end-of-chapter exercises that allow readers to practice and learn the skills associated with PBPK modeling, dose-response, and its applications to safety and risk assessments, this book is a foundational resource that provides practical coverage of PBPK modeling for graduate students, academics, researchers, and more. - Provides end-of-chapter exercises to teach hands-on computational tools used in toxicology - Supplies computer code and explanations and includes examples of applied models used in regulatory toxicology and research - Authored by expert editors and contributors who are among the best PBPK modelers in the world
Thick Concepts
An international team of experts explores the distinction between 'thin' concepts (general, evaluative terms like 'good' and 'bad') and 'thick' concepts (more specific concepts, such as 'brave', or 'rude'). Their essays touch on key debates in metaethics about the evaluative and normative, and raise fascinating questions about how language works.
Power and Society in the GDR, 1961-1979
The communist German Democratic Republic was founded in 1949 in the Soviet-occupied zone of post-war Germany. This book looks at its history and how people came to terms with their new lives behind the Wall. In the 1960s and 1970s, a fragile stability emerged characterized by 'consumer socialism', international recognition and détente. Growing participation in the micro-structures of power, and conformity to the unwritten rules of an increasingly predictable system, suggest increasing accommodation to dominant norms and conceptions of socialist 'normality.' These essays explore the ways in which lower-level functionaries and people at the grass roots contributed to the formation and transformation of the GDR ? from industry and agriculture, through popular sport and cultural life, to the passage of generations and varieties of social experience.
Being a State and States of Being in Highland Georgia
The highland region of the republic of Georgia, one of the former Soviet Socialist Republics, has long been legendary for its beauty. It is often assumed that the state has only made partial inroads into this region, and is mostly perceived as alien. Taking a fresh look at the Georgian highlands allows the author to consider perennial questions of citizenship, belonging, and mobility in a context that has otherwise been known only for its folkloric dimensions. Scrutinizing forms of identification with the state at its margins, as well as local encounters with the erratic Soviet and post-Soviet state, the author argues that citizenship is both a sought-after means of entitlement and a way of guarding against the state. This book not only challenges theories in the study of citizenship but also the axioms of integration in Western social sciences in general.
Law against the State
This collection of rich, empirically grounded case studies investigates the conditions and consequences of 'juridification' - the use of law by ordinary individuals as a form of protest against 'the state'. Starting from the actual practices of claimants, these case studies address the translation and interpretation of legal norms into local concepts, actions and practices in a way that highlights the social and cultural dynamism and multivocality of communities in their interaction with the law and legal norms. The contributors to this volume challenge the image of homogeneous and primordially norm-bound cultures that has been (unintentionally) perpetuated by some of the more prevalent treatments of law and culture. This volume highlights the heterogeneous geography of law and the ways boundaries between different legal bodies are transcended in struggles for rights. Contributions include case studies from South Africa, Malawi, Sierra Leone, Turkey, India, Papua New Guinea, Suriname, the Marshall Islands and Russia.
