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This is the first book to address all aspects of the biology of autoantibodies in a single volume, including a discussion of immunology, experimental models, clinical aspects, and the use of autoantibodies as probes in molecular and cellular biology. The editor, currently professor at the W.M. Keck Autoimmune Disease Center of The Scripps Research Institute, has assembled an all-star team of authors to report on the latest research, technologies, and applications. Following an introductory chapter, the book goes on to cover such topics as cellular mechanisms of autoantibody production, clinical and diagnostic usefulness in human disease, and animal models used to study the elicitation of autoantibodies. The whole is rounded off with a look at future perspectives. With its comprehensive coverage, this volume will appeal not only to immunologists and clinicians but also to cell and molecular biologists.
Thyroid Diseases is a comprehensive reference supported by a useful selection of schematic diagrams, tables, and charts. Its basic science section supplements classic and recent reviews of the subject by discussing structural and functional aspects of the thyroid gland, including thyroid hormone action (receptor and non-receptor mediated) and the hypothalamic-pituitary-thyroid control mechanisms. The clinical aspect of the book critically reviews current diagnostic modalities and addresses the choice of specialized tests and optimal sequence of their performance. Diagnostic modalities discussed include in vitro radioisotopic and nonradioisotopic assays of thyroid hormone, TSH, thyroglobulin, calcitonin, and autoantibodies. The various techniques are evaluated to show which procedures are applicable for each condition. This book brings together information dispersed across the medical and radiological literature. It will benefit professionals in radiology, nuclear medicine, and endocrinology, as well as students in these fields.
Autoimmunity is the most common cause of endocrine disorders. This volume provides an up-to-date summary of recent advances in this important field. In addition, it describes developments in our understanding of conditions such as vitiligo and pernicious anaemia which are frequently associated with autoimmune endocrinopathies. There is a detailed review of animal models of endocrine disease which have contributed greatly to current knowledge. Furthermore, the aetiology, pathogenesis and treatment of the clinical disorders are discussed in depth. The book will be of interest to anyone working in the areas of endocrinology and immunology.
Under the editorial leadership of Dr Gerald Litwack, Vitamins and Hormones continues to publish up-to-date synthetic reviews of interest to endocrinologists and biochemists. Others interested in the structure and function of biologically active molecules, like hormones and vitamins, will increasingly turn to this successful series for comprehensive reviews by leading contributors to this and related disciplines.
All the important pharmacological interactions affecting thyroid function are described in this book. The first section is devoted to the physiology and biochemistry of thyroid disease, putting the pharmacological interactions into perspective. The second section reviews all the important pharmacological effects on thyroid function and also deals with the impact of other environmental agents. The chapters are written by internationally recognised experts and extensively referenced to provide an up-to-date review of the pharmacological interactions important to the thyroid and its diseases.
This proceedings volume contains the transactions of a special meeting held with a view to considering the most important and distinctive advances in clinical research brought about by developments in molecular biology.
The neuroendocrine system plays a pivotal role in the control of growth, puberty, reproduction, and intermediate metabolism. This title presents the research on neuroendocrine physiology, advances in the control of the onset of puberty and its disorders, and basic and clinical aspects of the GH/IGF-1 and hypothalamic-pituitary-adrenal axes.
Each issue lists papers published during the preceding year.
Peptide Hormones—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Peptide Hormones. The editors have built Peptide Hormones—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Peptide Hormones in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Peptide Hormones—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Gluconeogenesis, the metabolic process through which glucose or glycogen is synthesized from noncarbohydrate substrates, is critical for maintaining the plasma glucose level within a narrow range either in the fed or fasting (nutritional deprivation) state. Dysregulation of this pathway usually causes severe or even fatal outcomes. This book discusses a series of up-to-date topics about this critical process, including the fundamental biochemical reactions of glucose metabolism, the glucogenesis process in eukaryotic cells using the Dictyostelium discoideum as a model, the role of "gut-brain-liver axis" in the control of glucose homeostasis, and the new mathematic model for the monitoring and prediction of blood glucose. This book is written by international scientists with expertise in the study of gluconeogenesis. By presenting a clear and succinct review of the fundamentals of gluconeogenesis, it is expected to draw more attentions and stimulate more scientists to dedicate their researches in revealing the mechanism and its application of gluconeogenesis.