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Regulation of Gene Expression and Brain Function
Gene expression converts the information coded by our genes into proteins. These determine the structure and function of an organ such as the brain. Itis therefore an essential process, linking molecular genetics with neurochemistry and behavioral neuroscience. This volume presents a didactic approach to the understanding of the basic processes of gene expression and their involvement in certain brain diseases, such asAlzheimer's disease and schizophrenia. Generously illustrated, the contributions provide a valuable outline of this key aspect of molecular neurobiology and clinical neuroscience.
Yearbook of Experts 2008
The Yearbook of Experts is a sourcebook of experts for news media interview. Published since 1984 is the America's Favorite Newsroom Reference.
Human African Trypanosomiasis (Sleeping Sickness)
As it is a goal to eliminate human African trypanosomiasis (HAT; sleeping sickness) as a public health problem by 2020 and interrupt transmission by 2030, this is a good moment to reflect on what we have achieved, what we want to achieve, and what could get in our way. HAT has a reputation for spectacular reappearances, and the latest peak of 40,000 reported and over 300,000 estimated cases only dates back to 1998. Efforts of the WHO and partners as well as the development of simpler and much better-tolerated treatments, improved diagnostics, and vector control tools made it possible to reduce this number by 95%. Case identification and confirmation remain complex and require specific skills...
Anaerobes in Biotechnology
This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.
Gene Editing
Gene-editing technologies (e.g., ZFNs, TALENs, and CRISPRs/Cas9) have been extensively used as tools in basic research. They are further applied in manufacturing agricultural products, food, industrial products, medicinal products, etc. Particularly, the discovery of medicinal products using gene-editing technologies will open a new era for human therapeutics. Though there are still many technical and ethical challenges ahead of us, more and more products based on gene-editing technologies have been approved for marketing. These technologies are promising for multiple applications. Their development and implications should be explored in the broadest context possible. Future research directions should also be highlighted. In this book, the applications, perspectives, and challenges of gene-editing technologies are significantly demonstrated and discussed.
