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Pharmaceutical Process Chemistry
Covering the whole area of process chemistry in the pharmaceutical industry, this monograph provides the essential knowledge on the basic chemistry needed for future development and key industrial techniques, as well as morphology, engineering and regulatory compliances. Application-oriented and well structured, the authors include recent examples of excellent industrial production of active pharmaceutical ingredients.
Experimental and Clinical Reconstructive Microsurgery
Since the first successful digit replantation in Japan in 1965, the field of microvascular surgery has rapidly progressed throughout Japan and the world. Experimental and Clinical Reconstructive Microsurgery draws on the experience of a large number of experts in the areas of experimental microsurgery, limb and digit replantation, and composite tissue transplantation. The result is an extensive monograph covering the history and future prospects of microsurgery, essential microsurgical techniques for laboratory research, and the fundamental methods of harvesting tissues and their grafting techniques. Because the field of microsurgery includes a broad range of clinical disciplines, this book is a valuable resource to all orthopedic, traumatic, and plastic surgeons with an interest in microsurgery.
Flavor Chemistry
Celebrating the founding of the Flavor Subdivision of the Agriculture and Food Chemistry Division of the American Chemical Society, this book provides an overview of progress made during the past 30-40 years in various aspects of flavor chemistry as seen by internationally renowned scientists in the forefront of their respective fields. In addition, it presents up-to-date findings in the areas of flavor chemistry, analytical methods, thermally produced flavors and precursors, enzymatically produced flavors and precursors, and sensory methods and results.
Drug Transporters
It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.
Drug Delivery
Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference. • Helps readers understand progress in drug delivery research and applications • Updates and expands coverage to reflect advances in materials for delivery vehicles, drug delivery approaches, and therapeutics • Covers recent developments including transdermal and mucosal delivery, lymphatic system delivery, theranostics • Adds new chapters on nanoparticles, controlled drug release systems, theranostics, protein and peptide drugs, and biologics delivery
Bioceramics Volume 10
Bioceramics 10 contains the proceedings of the 10th International Symposium on Ceramics in Medicine, held in Paris, France, in October 1997. These annual symposia bring together distinguished researchers in the fields of ceramics and medicine to exchange ideas and to discuss recent research results. Bioceramics in medicine has become one of the more important fields of biomaterials. The clinical applications of bioceramics are numerous. In particular in areas such as orthopaedic surgery, dentistry and plastic surgery, but also E.N.T., percutaneous devices and embolisation materials. In addition to the many clinical applications, Bioceramics 10 deals with a range of fundamental subjects in depth. This book will be an essential reference tool for both clinicians, academics and industrial researchers interested in the use of ceramics in medicine. The book will also be of great value to students and lecturers in materials science, biomedical engineering and orthopaedics. This volume contains 140 papers, more than 200 high quality photographs, and both author and keyword indexes.
Brewing Microbiology
Much has happened in the brewing industry since the last edition of this book was published in 1996. In particular, there has been substantial con solidation of larger brewing companies as major multinational concerns, and at the other end of the spectrum the microbrewing scene in various parts of the world has become established as a sustainable enterprise. For those involved in the scientific and technical aspects of fermented bever age production the changes have been no less daunting. The complete genome sequence of Saccharomyces cerevisiae has been determined and studies are underway in numerous laboratories throughout the world to unravel the expression of the genome (transcriptomics a...
New Insights into Fibromyalgia
Given the potential problems that can obscure any scientific enterprise, inconsistent results across studies are bound to occur. How are we to decide what is true? Let's turn to philosophy for a reasonable answer. The mathematician-philosopher Bertrand Russell approached a similar problem in his monograph The Problems of Philosophy (Russell B, 1912). He addressed the following question: How do we know that anything is "real"? Is the only reality subjective and simply in our minds, as Bishop Berkley challenged, or can we mostly believe the objective reality? His pragmatic answer: All possibilities may be true, but when the preponderance of evidence indicates that objective reality and knowledge are the most probable case, go with it. If the preponderance of all evidence about the clinical description of fibromyalgia and it's pathogenic mechanisms and treatment strategies indicate a highly probable interrelated hypothesis, go with it. The direction of the literature on the whole trumps the less likely tangents. At the same time, remember Bertrand Russell and his pragmatic answer, and keep an open mind.
Shape Memory Alloys
In the last decades, the Shape Memory Alloys, with their peculiar thermo-mechanical properties, high corrosion and extraordinary fatigue resistance, have become more popular in research and engineering applications. This book contains a number of relevant international contributions related to their properties, constitutive models and numerical simulation, medical and civil engineering applications, as well as aspects related to their processing.
