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The Koreans in Hawaii
The Koreans in Hawaii: A Pictorial History, 1903-2003, brings together hundreds of photographs to tell the powerful story of the people who have shaped the Korean immigrant experience in America over the past one hundred years. Although Koreans faced the same hardships and barriers as other East Asian immigrants in the New World, the story of their migration, settlement, and assimilation into American society has received relatively little attention. This volume not only commemorates the centennial of Koreans in Hawaii, but also offers readers an unprecedented look at the rich history of a community that continues to develop and change to this day. The photographs, which illuminate and complement writings and oral histories found elsewhere, provide insight into Hawaii's Korean immigrant community, politics, and everyday life. They reveal the struggles and successes of the first and subsequent generations, allowing viewers to connect with the past. Together with chapter introductions, the wide range of photographs (many only recently discovered in archives and family albums) represents an engaging record that uncovers the deep roots of Korean Americans in Hawaii.
The Korean Frontier in America
Korean immigration to Hawaii provides a striking glimpse of the inner workings of Yi-dynasty Korea in its final decade. It is a picture of confusion, functionalism, corruption, oppression, and failure of leadership at all levels of government. Patterson suggests that the weakness of the Korean government on the issue of emigration made it easier for Japanese imperialism to succeed in Korea. He also revises the standard interpretation of Japanese foreign policy by suggestion that prestige—the need to prevent the United States from passing a Japanese exclusion act—as well as security was a motivating factor in the establishment of a protectorate over Korea in 1905. In the process he uncove...
Catalytic RNA
This special volume of Progress in Molecular Biology and Translational Science focuses on catalytic RNA. Written by experts in the field, the reviews cover a range of topics, from hammerhead ribozymes to spliceosome catalysis to Varkud satellite and hairpin ribozymes. - Contributions from leading authorities - Informs and updates on all the latest developments in the field
Free Energy Calculations in Rational Drug Design
Free energy calculations represent the most accurate computational method available for predicting enzyme inhibitor binding affinities. Advances in computer power in the 1990s enabled the practical application of these calculations in rationale drug design. This book represents the first comprehensive review of this growing area of research and covers the basic theory underlying the method, numerous state of the art strategies designed to improve throughput and dozen examples wherein free energy calculations were used to design and evaluate potential drug candidates.
Computational Methods for Understanding Riboswitches
This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers computational prediction RNA structure and dynamics, including such topics as computational modeling of RNA secondary and tertiary structures, riboswitch dynamics, and ion-RNA, ligand-RNA and DNA-RNA interactions. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers computational methods and applications in RNA structure and dynamics - Contains chapters with emerging topics such as RNA structure prediction, riboswitch dynamics and thermodynamics, and effects of ions and ligands.
Annual Reports in Computational Chemistry
Annual Reports in Computational Chemistry is a new periodical providing timely and critical reviews of important topics in computational chemistry as applied to all chemical disciplines. Topics covered include quantum chemistry, molecular mechanics, force fields, chemical education, and applications in academic and industrial settings. Each volume is organized into (thematic) sections with contributions written by experts. Focusing on the most recent literature and advances in the field, each article covers a specific topic of importance to computational chemists. Annual Reports in Computational Chemistry is a "must" for researchers and students wishing to stay up-to-date on current developments in computational chemistry. Broad coverage of computational chemistry and up-to-date information Topics covered include bioinformatics, drug discovery, protein NMR, simulation methodologies, and applications in academic and industrial settings Each chapter reviews the most recent literature on a specific topic of interest to computational chemists
Topics in Anti-Cancer Research
This is the third volume of the Patent eBook Series entitled Topics in Anti-Cancer Research. This eBook comprises updated reviews on topics relevant to modern cancer research published in the journal Recent Patents on Anti-Cancer Drug Discovery. The comprehensive range of themes covered in this third volume will be of benefit to clinicians, scientists and R&D experts looking for new targets for the prevention of cancer and discovery of drugs for the treatment of different cancer types. Regulation of tumor cells by TRAIL receptors, development of anti- cancer drugs & immunomodulatory drugs, molecular studies of adrenocortical cancer, role of inhibitors of inosine monophosphate dehydrogenase i...
Computational Methods for Macromolecules: Challenges and Applications
This special volume collects invited articles by participants of the Third International Workshop on Methods for Macromolecular Modeling, Courant Institute of Mathematical Sciences, Oct. 12-14, 2000. Leading developers of methods for biomolecular simulations review advances in Monte Carlo and molecular dynamics methods, free energy computational methods, fast electrostatics (particle-mesh Ewald and fast multipole methods), mathematics, and molecular neurobiology, nucleic acid simulations, enzyme reactions, and other essential applications in biomolecular simulations. A Perspectives article by the editors assesses the directions and impact of macromolecular modeling research, including genomics and proteomics. These reviews and original papers by applied mathematicians, theoretical chemists, biomedical researchers, and physicists are of interest to interdisciplinary research students, developers and users of biomolecular methods in academia and industry.
