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In the last twenty years, many attempts have been made to provide neurobiological models of autism. Functional, structural and connectivity analyses have highlighted reduced responses in key social areas, such as amygdala, medial prefrontal cortex, cingulate cortex, and superior temporal sulcus. However, these studies present discrepant results and some of them have been questioned for methodological limitations. The aim of this research topic is to present advanced neuroimaging methods able to capture the complexity of the neural deficits displayed in autism. This special issue presents new studies using structural and functional MRI, as well as magnetoencephalography, and novel protocols to analyze data (Analysis of Cluster Variability, Noise Reduction Strategies, Source-based Morphometry, Functional Connectivity Density, Restriction Spectrum Imaging and the others). We believe it is time to integrate data provided by different techniques and methodologies in order to have a better understanding of autism.
The story of a neural impulse and what it reveals about how our brains work We see the last cookie in the box and think, can I take that? We reach a hand out. In the 2.1 seconds that this impulse travels through our brain, billions of neurons communicate with one another, sending blips of voltage through our sensory and motor regions. Neuroscientists call these blips “spikes.” Spikes enable us to do everything: talk, eat, run, see, plan, and decide. In The Spike, Mark Humphries takes readers on the epic journey of a spike through a single, brief reaction. In vivid language, Humphries tells the story of what happens in our brain, what we know about spikes, and what we still have left to u...
The Neuropsychology of Autism provides an up-to-date summary on the neuropsychology of autism spectrum disorders (ASD), written by leaders in the field. It summarizes current knowledge about neurochemistry, neuroanatomy, genetics, and clinical presentations and provides helpful discussions on key functions such as language, memory, attention, executive functions, social cognition, motor and sensory functioning.
A philosopher argues that we know little about our own inner lives. Do you dream in color? If you answer Yes, how can you be sure? Before you recount your vivid memory of a dream featuring all the colors of the rainbow, consider that in the 1950s researchers found that most people reported dreaming in black and white. In the 1960s, when most movies were in color and more people had color television sets, the vast majority of reported dreams contained color. The most likely explanation for this, according to the philosopher Eric Schwitzgebel, is not that exposure to black-and-white media made people misremember their dreams. It is that we simply don't know whether or not we dream in color. In Perplexities of Consciousness, Schwitzgebel examines various aspects of inner life (dreams, mental imagery, emotions, and other subjective phenomena) and argues that we know very little about our stream of conscious experience. Drawing broadly from historical and recent philosophy and psychology to examine such topics as visual perspective, and the unreliability of introspection, Schwitzgebel finds us singularly inept in our judgments about conscious experience.
An exploration of polyphony and the perspective it offers on our own polyphonic brains. Polyphony—the interweaving of simultaneous sounds—is a crucial aspect of music that has deep implications for how we understand the mind. In Polyphonic Minds, Peter Pesic examines the history and significance of “polyphonicity”—of “many-voicedness”—in human experience. Pesic presents the emergence of Western polyphony, its flowering, its horizons, and the perspective it offers on our own polyphonic brains. When we listen to polyphonic music, how is it that we can hear several different things at once? How does a single mind experience those things as a unity (a motet, a fugue) rather than ...
This graduate level textbook provides a coherent introduction to the body of main-stream algorithms used in electromagnetic brain imaging, with specific emphasis on novel Bayesian algorithms. It helps readers to more easily understand literature in biomedical engineering and related fields and be ready to pursue research in either the engineering or the neuroscientific aspects of electromagnetic brain imaging. This textbook will not only appeal to graduate students but all scientists and engineers engaged in research on electromagnetic brain imaging.
Secrets of Creativity combines insights from an interdisciplinary group of experts to reveal the secrets of creativity that emerge from our everyday lives, and from the minds of exceptional individuals and their discoveries. Neuroscientists describe the functioning of the brain in creative acts of scientific discovery or artistic production. Humanists describe the workings of the creative mind in the composition of literary works and in works of art and music. Creativity is explored with respect to forms of intelligence, modes of experience, emotions, memory, and the interplay between the brain's nonconscious and conscious system activities.
The complexity of the brain and the protean nature of behavior remain the most elusive area of science, but also the most important. van Hemmen and Sejnowski invited 23 experts from the many areas--from evolution to qualia--of systems neuroscience to formulate one problem each. Although each chapter was written independently and can be read separately, together they provide a useful roadmap to the field of systems neuroscience and will serve as a source of inspirations for future explorers of the brain.
Selected articles from Volume 5 Number 8 of the full 40-page print edition of the international autism newsletter, Looking Up.