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Kindling 5
The last Kindling Conference was organized by Dr. Juhn Wada and held at the Univer sity of British Columbia, Vancouver, B. C. , in 1989. In the intervening years, research on kin dling has proceeded at an explosive pace and significant advances have been made in our understanding of the molecular biological, anatomical, and physiological substrates of kin dling, as well as in our appreciation of the age-dependent effects and complex behavioral consequences of kindling, its sensitivity to drugs, and its relevance to the clinical epilepsies. In order to review these developments and to provide researchers with an opportunity to in teract face to face and discuss the issues that preoccupy us al...
Febrile Seizures
Febrile seizures are the most common seizures in infants and children worldwide, This fact provides strong impetus to study and understand them and their consequences, and consider their treatment. These topics were the focus of the first edition of this book. The 20 years since the publication of this first edition have witnessed an explosion of new information about febrile seizures, meriting this new edition. Key advances have been made in the genetics and neurobiological underpinnings of febrile seizures and especially the very long fever-related seizures called febrile status epilepticus. The role of neuroinflammatory factors in the emergence of these seizures and their consequences, th...
Synaptic Plasticity and Transsynaptic Signaling
Brain functions are realized by the activity of neuronal networks composed of a huge number of neurons. The efficiency of information transfer within the networks is changeable. Even the networks themselves can change through experience. Information transfer between neurons is performed at the synapse (the site of the neurons’ contact) by release of neurotransmitters from the pre-synaptic cell and capture of neurotransmitters by the post-synaptic cell. The amount of released neurotransmitter or the efficacy of capture can change. Moreover, synapses are found to be newly formed upon activity or abandoned upon inactivity. These changes are called "synaptic plasticity". This text focuses on one component of synaptic plasticity called transsynaptic signaling, or communication of synapses during their formation.
Epilepsy
The most up-to-date reference on the topic, Epilepsy analyzes the most relevant research developments in parallel clinical issues impacting modern therapeutic regimens-defining the scientific basis of current clinical practices and posing a set of challenging questions and considerations that may impact the future of clinical epilepsy research and
The CRF Signal
"Information molecules such as corticotropin-releasing factor (CRF) are ancient and widely distributed across diverse organs. The scientific community is beginning to realize that CRF is a dynamic and diversely widespread peptide hormone (e.g. placenta) with many functions (parturtion, metamorphosis, circadian rhythmicity) beyond acting as a releasing factor in the brain. Indeed, CRF has been associated with a range of states of the brain, including fear and anxiety, social contact, and incentive salence and addiction. Examining the evolutionary origins of CRF, its diverse endocrine and neural functions, this book provides insights into CRF that will be of interest to students and researchers in the biological, medical and behavioral sciences."--Page 4 of cover.
Recent Advances in Epilepsy Research
Epilepsy research has entered an exciting phase as advances in molecular analysis have supplemented in vitro and in vivo electrophysiologic and phenotypic characterization. Recent Advances in Epilepsy Research sets forth a series of chapter reviews by researchers involved in these advances. This volume is a composite profile of some exciting recent investigations in select areas of enquiry. Key features: neurogenetics of seizure disorders, new developments in cellular and molecular neurobiology of seizure disorders, the role of growth factors in seizures, new advances in the roles of metabotropic glutamate receptors and GABA receptors and transporters, gap junctions, neuroimmunology of epile...
The Epilepsies 3
This title in the acclaimed Blue Books of Neurology series highlights advances in epileptology and new ways of managing seizure disorders. Contributors from around the world-most new to this volume-lend a global perspective and provide the latest thinking on the new and controversial issues surrounding epilepsy. You'll find detailed discussions of difficulties in diagnosing and treating epilepsy, including the latest pharmacologic management strategies. This book covers the entire range of issues in epilepsy from basic science research to current clinical issues to medical and surgical therapeutics. Find all you need on critical issues in treating epilepsy and seizure disorders. Provides the...
100 Ways in 100 Days to Teach Your Baby Maths
Maths ability on entry to school is the strongest predictor of later academic achievement, double that of literacy skills, and simply saying more number words to babies increases their maths ability. What else have scientists, psychologists and professors learned about maths for babies? Babies seem to be born with an amazing number sense: understanding shapes in the womb, being aware of quantities at seven hours old, calculating probability at six months old, and doing addition and subtraction at nine months old. The best time to introduce maths is infancy. By the time children enter school there is already a significant gap in maths skills, this gap increases over time. A parent’s attitud...
Exploring Medical Biotechnology- in vivo, in vitro, in silico
This book on medical biotechnology offers a wide array of topics and cutting-edge research in the field featuring contributions from multiple authors, each specializing in their respective areas, making it highly valuable to science students and enthusiasts. The book provides comprehensive coverage on a diverse range of topics including sequence analysis, network pharmacology, drug discovery, CRISPR-Cas technology, precision medicine, neuroimaging biomarkers, therapeutics for neurodegenerative diseases, molecular pathogenesis of various diseases, plant-derived antioxidants, genetic approaches for disease diagnosis, cancer progression, immunotherapy, cancer biomarker identification, RNA Inter...
