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High-Resolution Profiling of Protein-RNA Interactions
The work reported in this book represents an excellent example of how creative experimentation and technology development, complemented by computational data analysis, can yield important insights that further our understanding of biological entities from a systems perspective. The book describes how the study of a single RNA-binding protein and its interaction sites led to the development of the novel ‘protein occupancy profiling’ technology that for the first time captured the mRNA sequence space contacted by the ensemble of expressed RNA binders. Application of protein occupancy profiling to eukaryotic cells revealed that extensive sequence stretches in 3’ UTRs can be contacted by R...
Legislative Document
None
Restoration and Management of Lakes and Reservoirs
It has been more than ten years since the last edition of the bestselling Restoration and Management of Lakes and Reservoirs. In that time, lake and reservoir management and restoration technologies have evolved and an enhanced version of this standard resource is long overdue. Completely revised and updated, the third edition continues the
22 Dutch Road
An estranged son drives twelve hours to collect badly needed money from his father's estate. The same ugly McMansion still sits behind a security wall, but there are new features: a gaudy slate roof, a 70s-style conversation pit, and nearly two dozen statues posted along the wall like sentinels. It makes no sense; Billy Buchanan's father was broke. Where had these fierce looking, valuable sculptures come from? Forced to spend the week at 22 Dutch Road, Billy begins believing these samurai-styled carvings can talk to him by day, and worse, move at night-his father might not be so dead after all.
