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High-Resolution Profiling of Protein-RNA Interactions
The work reported in this book represents an excellent example of how creative experimentation and technology development, complemented by computational data analysis, can yield important insights that further our understanding of biological entities from a systems perspective. The book describes how the study of a single RNA-binding protein and its interaction sites led to the development of the novel ‘protein occupancy profiling’ technology that for the first time captured the mRNA sequence space contacted by the ensemble of expressed RNA binders. Application of protein occupancy profiling to eukaryotic cells revealed that extensive sequence stretches in 3’ UTRs can be contacted by R...
Dissecting Regulatory Interactions of RNA and Protein
The work described in this book is an excellent example of interdisciplinary research in systems biology. It shows how concepts and approaches from the field of physics can be efficiently used to answer biological questions and reports on a novel methodology involving creative computer-based analyses of high-throughput biological data. Many of the findings described in the book, which are the result of collaborations between the author (a theoretical scientist) and experimental biologists and between different laboratories, have been published in high-quality peer-reviewed journals such as Molecular Cell and Nature. However, while those publications address different aspects of post-transcriptional gene regulation, this book provides readers with a complete, coherent and logical view of the research project as a whole. The introduction presents post-transcriptional gene regulation from a distinct angle, highlighting aspects of information theory and evolution and laying the groundwork for the questions addressed in the subsequent chapters, which concern the regulation of the transcriptome as the primary functional carrier of active genetic information.
The Role of Protein Post-Translational Modifications in Protein-RNA Interactions and RNP Assemblies
Dr. Nicolas Lux Fawzi is a member of the Scientific Advisory Board of Dewpoint Therapeutics LLC. All other Topic Editors declare no competing interests with regards to the Research Topic.
Buffalo City Directory
Historical papers are prefixed to several issues.
The Neuropsychology Handbook
ìA fantastic and monumental contribution to our field.î ñ Ralph M. Reitan, PhD "The field of neuropsychology has many specialized books on particular diseases, but there is always a need for a general text to cover the major aspects of neuropsychology from neuroanatomy to assessment to practice issues. This is one such book that attempts to provide comprehensive coverage of the field." --Doody's In the last decade, the number of books, courses, training opportunities, and journals dealing with clinical neuropsychology has greatly increased. Demand for a complete reference in the field is growing as practitioners in private practice, the court system, and the medical field continue to make...
The Neuropsychology Handbook
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Handbook of Forensic Neuropsychology
"This book brings together excellent contributions spanning the historic basis of neuropsychology in forensic practice, ethical and legal issues, and practical instruction....The editors have done an outstanding job in providing us with a volume that represents state-of-the-art in forensic neuropsychology. This volume also will be useful for graduate students, fellows, and practitioners in clinical neuropsychology." --Igor Grant, MD, Executive Vice Chair, UCSD Department of Psychiatry This book serves as an updated authoritative contemporary reference work intended for use by forensic neuropsychologists, psychiatrists, neurologists, neurosurgeons, pediatricians, attorneys, judges, law studen...
Autonomic Failure
This new edition makes diagnosis increasingly precise by fully evaluating the underlying anatomical and functional deficits, and continues to provide practitioners from a variety of fields with a rational guide to aid in the recognition and management of autonomic disorders.
