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First multi-year cumulation covers six years: 1965-70.
First multi-year cumulation covers six years: 1965-70.
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The discipline of neuroimmunomodulation is devoted to interactions between the immune nervous systems at all levels and includes observation on brain, pituitary, peripheral nervous system and immune cells. Nitric oxide synthase is contained within neurons in the brain and modifies behavioural and hormonal responses by acting on other neurons and on release of peptides and other transmitters through activation of guanylate cyclase and cyclooxygenase. Increases in this and in expression of proinflammatory cytokines can contribute to damage in patients with multiple sclerosis, Parkinsonism, meningitis, stroke, and Alzheimer's disease.
Affinity Chromatography and Biological Recognition contains manuscripts presented at the Fifth International Symposium on Affinity Chromatography and Biological Recognition convened in June 12-17, 1983, at St. John's College in Annapolis, Maryland. Organized into six parts encompassing 82 chapters, the book begins by examining the growing synergism between affinity methods and the understanding and study of basic principles of biological recognition. The book then focuses on the trends and progress in the design and application of affinity methods for isolation, therapeutics, diagnostics, and biotechnology. Significant chapters are devoted to the contributions of affinity methodology in such areas as cell membrane receptors, quantitative properties of macromolecular interactions, microscale analytical and preparative applications of high performance affinity chromatography, antibodies as in vivo and in vitro diagnostic and therapeutic agents, and drug targeting. This volume will be a stimulus for broad and creative application of affinity concepts and methods in many fields of biomedical research and biotechnology.