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Cell Communication and Signaling in Health and Disease
Cell communication and signaling are essential functions for life. The topic encompasses all basic and translational aspects of cellular communication and signaling pathways in normal and pathological conditions. Many diseases are the result of dysfunction in cell communication and signaling. This book presents contributions ranging from studies of sensory transduction, membrane receptors, ion channels, protein modification, cell transformation, receptor internalization, and trafficking to disease-oriented studies focusing on neurodegenerative diseases or cancer. As such, the book will provide a gateway for newly interested investigators and serve as a resource for seasoned researchers of cell biological phenomena in health and disease. Targeted at students and researchers in biological, medical, and chemical disciplines, this book will provide an overview of the work that is being done on this cell biology topic. The book highlights any gaps and areas that would benefit from further exploration pertaining to both intracellular and intercellular cell communication and signaling. In addition, the book will contribute to the training of current and future cell biologists.
Extracellular Vesicles
Extracellular vesicles (EVs) are nanoscale vesicles secreted by cells that mediate horizontal cargo transport from donor to recipient cell, thereby establishing cell-cell communication and signaling. This book provides critical information on the fundamentals of EVs, their roles in diseases like cancer, and their use in disease management. The chapters emphasize the emerging data confirming the role of EVs in the pathogenesis of diseases and discuss the scientific advances that have made it feasible to characterize and engineer EVs, leading to their use as tools in biomarker discovery and disease diagnosis, prognosis, therapeutic application, and theranostics. This volume is a valuable resource for basic biologists, translational scientists, and clinicians.
Human Physiology Annual Volume 2024
Human physiology is the scientific exploration of the various functions (physical, biochemical, and mechanical properties) of the human body, its organs, and its component cells. The endocrine and nervous systems play an important role in maintaining homeostasis in the human body. This book focuses on stroke-induced muscle atrophy, lung disease, and myocardial glycation, dealing respectively with their mechanisms, altered immune responses, and effects on epithelial cell physiology. Gut bacteria form a complex ecosystem through metabolite exchange with the host and are deeply involved in the pathogenesis of diseases (obesity, diabetes, cancer). The book also discusses research trends in gut bacteria and how to diagnose patients with amyloidosis. It will be of interest to professionals involved in clinical practice, as well as to medical and healthcare students and even researchers involved in human physiology.
Recent Advances in Homeostasis
The book presents a qualitative and quantitative approach to understanding, managing, and enforcing the integration of homeostasis in the human body. Homeostasis in the human body is very crucial, as it provides the basics of the normal functioning of the human body. Utilizing a sound theoretical and practical foundation and illustrating procedural techniques through scientific examples, this book bridges the gap between the need for understanding, utilizing, and going for detailed research in this aspect. Detailed procedures have been omitted because of the variety of equipment and commercial kits used in today’s clinical laboratories.
God, Guns, and Sedition
Shocking acts of terrorism have erupted from violent American far-right extremists in recent years, including the 2015 mass murder at a historic Black church in Charleston and the January 6, 2021, attack on the U.S. Capitol. These incidents, however, are neither novel nor unprecedented. They are the latest flashpoints in a process that has been unfolding for decades, in which vast conspiracy theories and radical ideologies such as white supremacism, racism, antisemitism, xenophobia, and hostility to government converge into a deadly threat to democracy. God, Guns, and Sedition offers the definitive account of the rise of far-right terrorism in the United States—and how to counter it. Leadi...
Mechanisms and Management of Senescence
Senescence represents a complex universal phenomenon that can be impacted by several factors. It is emerging as a therapeutic target for several diseases. This book presents an overview of the current mechanisms and management of senescence in humans. It also provides comparative data on senescence in animals and plants.
Topics in Autonomic Nervous System
The nervous system is an essential component of the human body and is divided into two main systems: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS is composed of the brain and the spinal cord and acts as the command center of the organism. The PNS is a network of nerves that extends from the spinal cord throughout the body and regulates both voluntary and involuntary movements, such as digestion, heart rate, breathing, and body temperature. Within the PNS, there are two subdivisions: the somatic nervous system and the autonomic nervous system. The somatic system controls voluntary movements, while the autonomic system operates automatically and regulates e...
Dietary Carotenoids
In recent years scientists have identified several biologically active compounds from plant and animal foods having beneficial health effects. Technically, they are not “nutrients,” despite having beneficial health properties. Instead, they are referred to as phytonutrients, nutraceuticals, and functional ingredients. Taking advantage of these compounds’ benefits, food, pharmaceutical, and cosmetic manufacturers now include them in their commercial products. However, unlike vitamins and minerals, they do not have recommended levels of daily intake. Consumers are simply advised to include foods and supplements that are good sources of these phytonutrients as part of a healthy diet. In g...
Plant Stress Physiology
This book includes ten chapters addressing various aspects of plant stress physiology, including plant responses and tolerance to abiotic and biotic stress. These chapters summarize recent findings on the physiological and molecular mechanisms of stress tolerance. They also discuss approaches to enhancing plant productivity via stress tolerance mechanisms. This book is useful for undergraduate and graduate students, teachers, and researchers in the field of plant physiology and crop science.
Potassium in Human Health
This is an introductory book on the role of potassium in health, physiology of potassium homeostasis, diagnostic approach to potassium derangement, and clinical management of potassium disorders. It is a concise, easy-to-read reference for students in the health professions, mid-level providers, house staff trainees, and clinicians.
