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Explains the multimodal connections of text, image, space, body, sound and speech, in both old and new computer-mediated communication systems.
The goal of enterprise integration is the development of computer-based tools that facilitate coordination of work and information flow across organizational boundaries. These proceedings, the first on EI modeling technologies, provide a synthesis of the technical issues involved; describe the various approaches and where they overlap, complement, or conflict with each other; and identify problems and gaps in the current technologies that point to new research.The leading edge of a movement that began with computer-aided design/computer-aided manufacturing (CAD/CAM), EI now seeks to engage the development of computer-based tools to control not only manufacturing but the allied areas of mater...
The earliest known member of this family, Marx (Markus) Engelhorn (1580-1650), was born in Hockenheim, Baden, Germany. The common ancestor of all the Engelhorns who came to Allamakee Co., Iowa between 1847 and 1866 was, Johann Marcus Engelhorn II (1782-1869), who was Bürger, farmer and magistrate in Altlussheim, Germany. He stayed in Germany. His oldest son, Johann Thomas III, also stayed in Germany, but eight of his nine surviving children immigrated to America as well as four Johann Thomas's siblings. Family members and descendants live in Iowa, Illinois, Minnesota, Montana, North Dakota, Ohio, California, Oregon and elsewhere.
Over the last two decades, satellite gravimetry has become a new remote sensing technique that provides a detailed global picture of the physical structure of the Earth. With the CHAMP, GRACE, GOCE and GRACE Follow-On missions, mass distribution and mass transport in the Earth system can be systematically observed and monitored from space. A wide range of Earth science disciplines benefit from these data, enabling improvements in applied models, providing new insights into Earth system processes (e.g., monitoring the global water cycle, ice sheet and glacier melting or sea-level rise) or establishing new operational services. Long time series of mass transport data are needed to disentangle ...
The five-volume set LNCS 3980-3984 constitutes the refereed proceedings of the International Conference on Computational Science and Its Applications, ICCSA 2006. The volumes present a total of 664 papers organized according to the five major conference themes: computational methods, algorithms and applications high performance technical computing and networks advanced and emerging applications geometric modelling, graphics and visualization information systems and information technologies. This is Part V.
New therapies are currently being developed in the field of skin cancer. In particular, advances in melanoma now represent the frontline of cancer immunotherapy, as immunological findings in the disease have led to the development of highly effective immune-checkpoint inhibitors. However, these immune-checkpoint inhibitors are only effective in a subset of patients, and may not work in other skin cancer types, thus highlighting the need for further innovation in the field of skin cancer treatment. The purpose of this Research Topic is therefore to provide an up-to-date overview of immune processes and new therapies for melanoma and other skin cancers in order to further stimulate the development of new and even more successful treatments.