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One Health High-Level Expert Panel Annual Report 2023
This report summarizes the activities and results achieved in 2023 by the 26 experts of the One Health High-Level Expert Panel (OHHLEP). [Author] The first term of OHHLEP, initially set to expire in June 2023, was extended until December 2023 to allow for the completion of remaining deliverables and for the preparation for a second Term of OHHLEP by the Quadripartite. [Author] The Quadripartite updated the OHHLEP Terms of Reference for a second two-year term to focus on the implementation of the One Health approach and the One Health Joint Plan of Action (OH JPA) and launched a call for expressions of interest to renew the membership of the OHHLEP. [Author]
One Health High-Level Expert Panel Annual Report 2022
This report summarizes the activities and results achieved in 2022 by the 26 experts of the One Health High-Level Expert Panel (OHHLEP). OHHLEP provided scientific advice on the Quadripartite One Health Joint Plan of Action (OH JPA) which was launched in October 2022, worked on a One Health Theory of Change that became an integral part of the OH JPA, prepared scientific opinions related to the envisaged Pandemic Instrument, and developed a white paper on the definition for the Prevention of zoonotic spillover. OHHLEP also continued to support the implementation of the Quadripartite OH JPA through development of an inventory of One Health tools. With these activities, OHHLEP supported the Quadripartite’s efforts on the mainstreaming and implementation of One Health. The report highlights main outputs and deliverables produced over the period and outlines priorities for 2023.
Evaluation of the Updated Site-Specific Risk Assessment for the National Bio- and Agro-Defense Facility in Manhattan, Kansas
Safeguarding U.S. agriculture from foreign animal diseases and protecting our food system require cutting-edge research and diagnostic capabilities. The Department of Homeland Security (DHS) and the U.S. Department of Agriculture (USDA) have embarked on an important mission to replace the aging Plum Island Animal Disease Center (PIADC) with a new facility, the National Bio- and Agro-Defense Facility (NBAF). When operational, this new facility would be the world's fourth biosafety level-4 laboratory capable of large animal research. It would serve as a critical world reference laboratory for identifying emerging and unknown disease threats, and would thus be a critical asset in securing the f...
Neuroanatomical Tract-Tracing
The first two editions of this title had a tremendous impact in neuroscience. Between the Second edition in 1989 and today, there has been an explosion of information in the field, including advances in molecular techniques, such as genomics and proteomics, which have become increasing important in neuroscience. A renaissance in fluorescence has occurred, driven by the development of new probes, new microscopes, live imagers, and computer processing. The introduction of new markers has enormously stimulated the field, moving it from tissue culture to neurophysiology to functional MRI techniques.
RNA Vaccines
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100 Years of Virology
One hundred years ago, when Martinus W. Beijerinck in Delft and Friedrich Loeffler on Riems Island discovered a new class of infectious agents in plants and animals, a new discipline was born. This book, a compilation of papers written by well-recognized scientists, gives an impression of the early days, the pioneer period and the current state of virology. Recent developments and future perspectives of this discipline are sketched against a historic background. With contributions by A. Alcami, D. Baulcombe, F. Brown, L. W. Enquist, H. Feldmann, A. Garcia-Sastre, D. Griffiths, M. C. Horzinek, A. van Kammen, H.-D. Klenk, F. A. Murphy, T. Muster, R. O'Neill, P. Palese, C. Patience, R. Rott, H.- P. Schmiedebach, S. Schneider-Schaulies, G. L. Smith, J. A. Symons, Y. Takeuchi, V. ter Meulen, P. J. W. Venables, V. E. Volchkov, V. A. Volchkova, R. A. Weiss, W. Wittmann, H. Zheng.
Avian Influenza
Because of its high impact on both animal and human health, avian influenza has become a matter of increasing public concern and growing scientific interest within the last decade. This volume gives an overview of the most important results of these research efforts and provides information about the ecology and epidemiology of avian influenza with particular emphasis on recent H5N1 outbreaks in China, Siberia and Europe. Several articles deal with new vaccination strategies, the use of antivirals and other control measures to combat outbreaks of avian influenza. Further chapters illustrate that molecular biology, culminating in the generation of influenza viruses by recombinant DNA technolo...
