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Logical Modeling of Cellular Processes: From Software Development to Network Dynamics
  • Language: en
  • Pages: 340

Logical Modeling of Cellular Processes: From Software Development to Network Dynamics

Mathematical models have become invaluable tools for understanding the intricate dynamic behavior of complex biochemical and biological systems. Among computational strategies, logical modeling has been recently gaining interest as an alternative approach to address network dynamics. Due to its advantages, including scalability and independence of kinetic parameters, the logical modeling framework is becoming increasingly popular to study the dynamics of highly interconnected systems, such as cell cycle progression, T cell differentiation and gene regulation. Novel tools and standards have been developed to increase the interoperability of logical models, which can now be employ to respond a variety of biological questions. This Research Topic brings together the most recent and cutting-edge approaches in the area of logical modeling including, among others, novel biological applications, software development and model analysis techniques.

The Impact of Systems Medicine on Human Health and Disease
  • Language: en
  • Pages: 98

The Impact of Systems Medicine on Human Health and Disease

Complex disorders including obesity, diabetes, fatty liver disease, cardiovascular disease and cancer are results from a combination of genetic, environmental and lifestyle factors. The prevalence of such disorders has increased dramatically in the last two decades and there is an urgent need for the development of new prognostic tools for the treatment of such diseases. However, this requires a deep understanding of the underlying molecular mechanisms involved in the occurrence of the diseases. With the advances in high throughput technologies, biological components of cells can be measured with a very high resolution and these data can be used for investigating whole systems properties usi...

The Poll Taxes of 1377, 1379, and 1381: Part 1: Bedfordshire-Leicestershire
  • Language: en
  • Pages: 698

The Poll Taxes of 1377, 1379, and 1381: Part 1: Bedfordshire-Leicestershire

  • Type: Book
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  • Published: 1998-06-11
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  • Publisher: OUP Oxford

Provides an intriguing and detailed picture of late fourteenth century EnglandPresents complex material in a clear formatThe English poll taxes of 1377, 1379, and 1381 taxed householders, wives, dependants, and servants individually. The tax records therefore provide information about people who are rarely, if ever, mentioned in other documents - frequently including details of occupations and relationships. The widely varying documents associated with the taxes are being published in three volumes, to make this massive resource accessible to social and economic historians, demographers, and genealogists. This first volume, which covers all three taxes for Bedfordshire to Leicestershire, includes extensive editorial descriptions of the documents, explanations of the collection and recording processes, and a discussion of the relevance and value of this exciting material. Full indexes of original and contemporary place names and a glossary of occupations will appear in the third volume.Readership: Scholars and students of medieval history, economic and social historians, local historians, genealogists.

Official Gazette of the United States Patent and Trademark Office
  • Language: en
  • Pages: 1420

Official Gazette of the United States Patent and Trademark Office

  • Type: Book
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  • Published: 2002
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  • Publisher: Unknown

None

The London Gazette
  • Language: en
  • Pages: 1512

The London Gazette

  • Type: Book
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  • Published: 1880
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  • Publisher: Unknown

None

Taxation of Derivatives and Cryptoassets
  • Language: en
  • Pages: 519

Taxation of Derivatives and Cryptoassets

  • Categories: Law

Derivatives stand at the forefront of financial innovation, continually evolving to accommodate new asset classes and risk categories. In the past decade, the growing popularity of cryptoassets and ESG investments has sparked the development of a variety of innovative investment strategies and risk management tools, including crypto and ESG derivatives and related structured products. This new edition has similarly evolved. Using illustrative examples, it provides a comprehensive analysis of the key tax issues associated with derivatives and cryptoassets in domestic and cross-border transactions and presents approaches that tax legislators could adopt to solve them. The new edition also comm...

Automated Reasoning for Systems Biology and Medicine
  • Language: en
  • Pages: 471

Automated Reasoning for Systems Biology and Medicine

  • Type: Book
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  • Published: 2019-06-11
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  • Publisher: Springer

This book presents outstanding contributions in an exciting, new and multidisciplinary research area: the application of formal, automated reasoning techniques to analyse complex models in systems biology and systems medicine. Automated reasoning is a field of computer science devoted to the development of algorithms that yield trustworthy answers, providing a basis of sound logical reasoning. For example, in the semiconductor industry formal verification is instrumental to ensuring that chip designs are free of defects (or “bugs”). Over the past 15 years, systems biology and systems medicine have been introduced in an attempt to understand the enormous complexity of life from a computat...

House Documents
  • Language: en
  • Pages: 1152

House Documents

  • Type: Book
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  • Published: 1868
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  • Publisher: Unknown

None

Miscellaneous Documents
  • Language: en
  • Pages: 1150

Miscellaneous Documents

  • Type: Book
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  • Published: 1868
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  • Publisher: Unknown

None

The Rochester Directory
  • Language: en
  • Pages: 430

The Rochester Directory

  • Type: Book
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  • Published: 1870
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  • Publisher: Unknown

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