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Regulation of Gene Expression by Small RNAs
New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it's been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In higher eukaryotes, microRNAs may regulate as much as 50 p
Molecular Medical Parasitology
A valuable, new source, Molecular Medical Parasitology is the only text of its kind -- one that applies broad concepts and current scientific advances from both molecular biology and biochemistry to the study of parasitic organisms. An internationally renowned team of scientists and physicians places parasites in their broad biological contexts while still emphasizing the specifics that differentiate these organisms. Not only will researchers and faculty in parasitology find this an indispensable guide, physicians will benefit from the thorough coverage molecular biology and biochemistry's current influences on treatment and management of parasitic diseases. - Features the most up-to-date scientific methods behind the medical management of parasitic diseases - Applies the most current synthesis of molecular biology and biochemistry to parasitic organisms - Contains many informative figures and clear illustrations
Behavior and Culture in One Dimension
Behavior and Culture in One Dimension adopts a broad interdisciplinary approach, presenting a unified theory of sequences and their functions and an overview of how they underpin the evolution of complexity. Sequences of DNA guide the functioning of the living world, sequences of speech and writing choreograph the intricacies of human culture, and sequences of code oversee the operation of our literate technological civilization. These linear patterns function under their own rules, which have never been fully explored. It is time for them to get their due. This book explores the one-dimensional sequences that orchestrate the structure and behavior of our three-dimensional habitat. Using Gib...
The Catalyst: RNA and the Quest to Unlock Life's Deepest Secrets
One of Literary Hub's Most Anticipated Books of 2024 Exploring the most transformative breakthroughs in biology since the discovery of the double helix, a Nobel Prize–winning scientist unveils the RNA age. For over half a century, DNA has dominated science and the popular imagination as the “secret of life.” But over the last several decades, a quiet revolution has taken place. In a series of breathtaking discoveries, the biochemist Thomas R. Cech and a diverse cast of brilliant scientists have revealed that RNA—long overlooked as the passive servant of DNA—sits at the center of biology’s greatest mysteries: How did life begin? What makes us human? Why do we get sick and grow old...
Alternative pre-mRNA Splicing
This book was written for graduate and medical students, as well as clinicians and postdoctoral researchers. It describes the theory of alternative pre-mRNA splicing in twelve introductory chapters and then introduces protocols and their theoretical background relevant for experimental research. These 43 practical chapters cover: Basic methods, Detection of splicing events, Analysis of alternative pre-mRNA splicing in vitro and in vivo, Manipulation of splicing events, and Bioinformatic analysis of alternative splicing. A theoretical introduction and practical guide for molecular biologists, geneticists,clinicians and every researcher interested in alternative splicing. Website: www.wiley-vch.de/home/splicing
