You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
This unique volume traces the critically important pathway by which a "molecule" becomes an "anticancer agent. " The recognition following World War I that the administration of toxic chemicals such as nitrogen mustards in a controlled manner could shrink malignant tumor masses for relatively substantial periods of time gave great impetus to the search for molecules that would be lethal to specific cancer cells. Weare still actively engaged in that search today. The question is how to discover these "anticancer" molecules. Anticancer Drug Development Guide: Preclinical Screening, Clinical Trials, and Approval, Second Edition describes the evolution to the present of preclinical screening met...
Beverly A. Teicher and a panel of leading experts comprehensively describe for the first time in many years the state-of-the-art in animal tumor model research. The wide array of models detailed form the basis for the selection of compounds and treatments that go into clinical testing of patients, and include syngeneic models, human tumor xenograft models, orthotopic models, metastatic models, transgenic models, and gene knockout models. Synthesizing many years experience with all the major in vivo models currently available for the study of malignant disease, Tumor Models in Cancer Research provides preclinical and clinical cancer researchers alike with a comprehensive guide to the selection of these models, their effective use, and the optimal interpretation of their results.
Explore the ways that work, welfare, and material hardship affect the mental health of low-income women! Welfare, Work, and Well-Being reflects a growing interest among the research, policy and media communities in the connections between the psychological and economic well-being of poor women and their families. The Personal Responsibility and Work Opportunity Act (PRWORA) of 1996, and the sharp declines in welfare caseloads that began even prior to the legislation, have changed the lives of poor women and children in critical ways. The social scientists in this volume investigate the associations among welfare, work, social roles, child well-being, material hardship, and women's mental hea...
The Other Side of the World: Vision and Reality embraces and celebrates the experiences of idealistic, young Peace Corps volunteers as they confronted the ancient and enigmatic civilization of India four decades ago. Prompted by memories and emotions tapped during a gathering on the 40-year reunion of their return to the States, members of India 44 A&B provide reflections that are honest, compelling, insightful, riotous, humbling, and yet redemptive. These reflections give expression to feelings long repressed and, at the same time, uncover the mysterious ways in which their service in remote India transformed and redirected the trajectory of their lives. Their stories provide a humorous and...
None
In The Boat Captains Conundrum, author Tom Corbett completes an intellectual journey that reflects on his four-plus decades as a scholar and doer of social policy. That journey starts with Ouch, Now I Remember in which he recounts his early days growing up in a closed, working class, ethnic community from which he underwent several transformative experiences that broadened his worldview. In Browsing Through My Candy Store, the author shared his struggles while confronting many of the most vexing poverty and welfare battles of the last half century. This final volume, the Boat Captains Conundrum, completes the trilogy. This work takes the reader on quite a different journey, a path that goes ...
This volume assembles hundreds of cases and studies to provide the most accurate and comprehensive picture of the status of pornography in the criminal justice system. Presenting high-level research in an accessible and organized manner, it explores a range of topics, including investigating and prosecuting a case, arguments favoring and opposing d
New thinking is needed on the age-old conundrum of how to connect research and policymaking. Why does a disconnect exist between the research community, which is producing thousands of studies relevant to public policy, and the policy community, which is making thousands of decisions that would benefit from research evidence? The second edition updates community dissonance theory and provides an even stronger, more substantiated story of why research is underutilized in policymaking, and what it will take to connect researchers and policymakers. This book offers a fresh look into what policymakers and the policy process are like, as told by policymakers themselves and the researchers who stu...
This book examines ways to enhance evidence-based policymaking, striking a balance between theory and practice. The attention to theory builds a greater understanding of why miscommunication and mistrust occur. Until we better appreciate the forces that divide researchers and policymakers, we cannot effectively construct strategies for bringing them together.
Gone are the days when researchers, policymakers, and practitioners each worked in isolation. In recent years, a few interrelated issues have emphasized the need for greater collaboration among researchers, policymakers and practitioners: the increased emphasis on results and accountability (particularly where public funds are at stake), the need to improve services, and the growing use of technology. This book is about these all-important partnerships, specifically the relationships between those searching for evidence and those who are putting evidence to use through designing and implementing policy at the federal, state, or local level. Students of public policy, public administration, social work, and education will find much to inform future roles in research, policy, or practice.