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Thyroid Diseases in Childhood
This book covers the entire spectrum of thyroid diseases in childhood, focusing on the recent advances that have been achieved, from progress in basic science research through to novel or improved approaches to diagnosis and treatment. Introductory chapters discuss thyroid embryogenesis and the role of thyroid hormones in fetal development. The two contrasting forms of thyroid dysfunction, hypo- and hyperthyroidism, are then considered in depth, with particular attention to the molecular causes of congenital hypothyroidism. Among the other topics addressed are autoimmune thyroiditis, thyroid nodules, and pediatric neoplasms. The book concludes with an overview of promising therapeutic approaches, such as stem cell therapy. Each topic is treated by an eminent expert in the field, ensuring consistently high quality. Thyroid Diseases in Childhood will be an important source of information for endocrinologists, pediatricians, oncologists, and gynecologists, as well as other professionals interested in this topic.
Virgil and His Translators
This is the first volume to offer a critical overview of the long and complicated history of translations of Virgil from the early modern period to the present day, transcending traditional studies of single translations or particular national traditions in isolation to offer an insightful comparative perspective. The twenty-nine essays in the collection cover numerous European languages - from English, French, and German, to Greek, Irish, Italian, Norwegian, Slovenian, and Spanish - but also look well beyond Europe to include discussion of Brazilian, Chinese, Esperanto, Russian, and Turkish translations of Virgil. While the opening two contributions lay down a broad theoretical and comparat...
Glucose Metabolism Derangements in Pediatric Age
This book addresses the difficult field of pediatric glycometabolic disorders, which have often been considered the exclusive field of specialists in the sector. However, if all the intricate subjects of long-term treatment of type 1 diabetes are certainly a specialist field, the diagnosis of type 1 diabetes or its distinction from other forms of diabetes cannot be considered fields of strict specialization. Indeed, hypoglycemia, metabolic syndrome due to obesity, and drug-induced hyperglycemia are not specialized fields. Instead, we often see the clinician withdrawing from these pathologies. This book provides the trainee pediatric specialist with robust preliminary knowledge of the field.
With Obesity Becoming the New Normal, What Should We Do?
Obesity is a global epidemic and an urgent health crisis impacting human health and health services, with the economic consequences of loss of human capital. It is a crisis for health professionals, health economists and government officials managing finite resources and the economy with premature loss of life and economic productivity. In this Frontiers Research Topic, researchers from a breadth of disciplines internationally contributed reviews, meta-analyses and novel data on the challenges obesity presents in attempts to stimulate debate on strategies and solutions for this crisis.
Short Stature: Beyond Growth Hormone
Short stature refers to a height less than two standard deviations below the mean for a given age and gender. The effective investigation of short stature pathology in children combines clinical assessment, to view symptoms and bodily dysfunctions; endocrine assessment, to determine hormone levels and sensitivity; and increasingly advanced genetic analysis. Many children of short stature do not have an identified underlying pathology, thus assigned as having idiopathic short stature (ISS). Consequently, the ISS population can be subdivided into those with ‘normal variants’ of growth, termed familial short stature (FSS) and non-familial short stature (NFSS), including constitutional delay of growth and puberty (CDGP). These categories can then separate from that of children with ISS who show a different etiology.
