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Toxoplasmosis of Animals and Humans
Found worldwide from Alaska to Australasia, Toxoplasma gondii knows no geographic boundaries. The protozoan is the source of one of the most common parasitic infections in humans, livestock, companion animals, and wildlife, and has gained notoriety with its inclusion on the list of potential bioterrorism microbes. In the two decades since the publi
Toxoplasma Gondii
This 2e of Toxoplasma gondii reflects the significant advances in the field in the last 5 years, including new information on the genomics, epigenomics and proteomics of T. gondii as well as a new understanding of the population biology and genetic diversity of this organism. T. gondii remains the best model system for studying the entire Apicomplexa group of protozoans, which includes Malaria, making this new edition essential for a broad group of researchers and scientists. Toxoplasmosis is caused by a one-celled protozoan parasite known as T. gondii. The infection produces a wide range of clinical syndromes in humans, land and sea mammals, and various bird species. Most humans contract to...
Toxoplasma gondii
For years, toxoplasmosis has been known as disease mostly affecting newborns. Since immunocompromised patients (AIDS) present a high risk of reactivation of chronic toxoplasmosis this parasitic disease has gained increasing interest. Besides presenting clinical and therapeutical concepts, this volume provides current knowledge about genetics and immunology of T. gondii and the interaction with its 'host'. Since in vivo and in vitro models of toxoplasmosis exist, and genetic manipulation has become possible, this protozoan parasite has recently been accepted as a model for understanding the pathogenesis and persistance of other intracellular parasites. The articles of the book compromise both reviewing current concepts and reporting on yet unpublished results of leading scientists in this field.
Toxoplasma Gondii Host Interactions: A Story of Immune Attack and Parasite Counterattack
Toxoplasma gondii is an obligate intracellular parasite that can infect all warm-blooded animals, including an estimated ~30% of humans. It can cause severe disease in immune-suppressed individuals and in fetuses as well as blinding chorioretinitis in adults and children. Toxoplasma-innate immune system interactions determine early parasite control and activation of the adaptive immune system by the host and are therefore critical in determining host survival during the acute phase of infection. However, induction of an exaggerated inflammatory response can also lead to pathology. Only the chronic tissue cyst form of Toxoplasma is orally infectious. It is therefore critical for the parasiteâ...
Toxoplasmosis
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Parasites, Pussycats and Psychosis
This open access book analyzes the evidence linking Toxoplasma gondii to the increasing incidence of schizophrenia and bipolar disorder in the United States. Initially establishing that infectious agents are regularly transmitted from animals to humans, lead to human disease, and that infectious agents can cause psychosis, it then examines the protozoan parasite Toxoplasma gondii in detail. Infecting 40 million Americans, Toxoplasma gondii is known to cause congenital infections, eye disease, and encephalitis for individuals who are immunosuppressed. It has also been shown to change the behavior of nonhuman mammals, as well as to alter some personality traits in humans. After discussing the ...
Toxoplasmosis
The most common latent protozoan infection in humans The infection is usually dangerous only in pregnancy or in an immunocompromised patient. The transmission is usually from cat faeces, soil, or inadequately cooked meat. Symptomatic disease is the consequence of a primary infection or the reactivation of a latent infection.
Toxoplasmosis
A ubiquitous organism able to infect all mammals and birds, which has been estimated to infect one third of the global human population, Toxoplasma gondii is the most successful parasite on Earth, and toxoplasmosis a major zoonotic disease. A current approach to this zoonosis is the "one health" concept, based on the understanding that a disease occurring between animals and man in a specific environment can only be dealt with at the interface of all "players" involved. This book, composed of a series of articles which integrate human and animal data on toxoplasmosis, by authors from all over the world, offers its readers a view on the current research interests and achievements.
