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Steroid Biochemistry
  • Language: en
  • Pages: 482

Steroid Biochemistry

  • Type: Book
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  • Published: 2023-10-07
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  • Publisher: Elsevier

Steroid Biochemistry, Volume 688 in the Methods of Enzymology series, highlights new advances in the field, containing chapters on a variety of timely topics, including Cytochrome P450 Enzyme, Steroidogenic P450s (CYP11A1, 17A1, 21A2, 11B1, and 11B5), Steroid 17 alpha-hydroxylase/17,20-lyase (Cytochrome P450 17A1), Enzymes of Estrogen Biosynthesis, Aromatase and Steroid Sulfatase, Estrogenic 17b-Hydroxysteroid Dehydrogenase, Hydroxysteroid Dehydrogenases (HSD), 3a-Hydroxyssteroid Dehydrogenase, Approaches to Measuring 3b-Hydroxysteroid Dehydrogenase Type 1, 3b-Hydroxysteroid Dehydrogenase Type 2, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods in Enzymology serials Updated release includes the latest information on Steroid Biochemistry

Aldo-Keto Reductases and Toxicant Metabolism
  • Language: en
  • Pages: 280

Aldo-Keto Reductases and Toxicant Metabolism

Aldo-Keto Reductases and Toxicant Metabolism provides an overview of the rapidly growing Aldo-Keto Reductase (AKR) superfamily and its role in the metabolism of endogenous and exogenous toxicants. This book discusses the ability of AKRs to metabolize endogenous toxicants including: sugar aldehydes, advanced glycosylation end products, and lipid aldehydes (products of lipid peroxidation decomposition). The relevance to diabetic complications is also stressed. The role of AKRs to metabolize exogenous toxicants including tobacco carcinogens (tobacco specific nitrosamine ketones and trans-dihydrodiols derived from polycyclic aromatic hydrocarbons), mycotoxins (aflatoxin dialdehydes), and unnatur...

Enzymology and Molecular Biology of Carbonyl Metabolism 13
  • Language: en
  • Pages: 428

Enzymology and Molecular Biology of Carbonyl Metabolism 13

The continuation of an annual series, Enzymology and Molecular Biology of Carbonyl Metabolism is the largest collection of articles on the three major gene families. The scope of the chapters, contributed by leading international scientists, is wide and covers gene regulation to enzyme mechanisms and protein structure. This is the only publication dealing in such depth with just three gene families. It is an important reference for researchers in toxicology and molecular biology.

Chemical Carcinogenesis
  • Language: en
  • Pages: 447

Chemical Carcinogenesis

This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many cancers. The multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action will be a focal point. The balance between metabolic activation to form biological reactive intermediates and their detoxification, ensuing DNA-lesions and their repair will be profiled. It will describe the chemical changes that occur in DNA that result from endogenous insults including epigenetic changes that lead to gene silencing. It will describe major mechanisms of mutagenesis, affects on tumor suppressor genes and proto-oncogenes, and how cell-cycle check points can be by-passed by the "stealth-like" properties of chemical carcinogens. Environmental agents that can promote tumor formation will be discussed. The monograph will have wide appeal as a knowledge base for graduate students, post-doctoral fellows and faculty interested in this aspect of cancer causation and research.

Research Grants
  • Language: en
  • Pages: 584

Research Grants

  • Type: Book
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  • Published: 1988
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  • Publisher: Unknown

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Targeted Inhibitors for Steroid Transforming Enzymes
  • Language: en
  • Pages: 161

Targeted Inhibitors for Steroid Transforming Enzymes

  • Type: Book
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  • Published: 2011
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  • Publisher: Unknown

None

Quinones and Quinone Enzymes, Part A
  • Language: en
  • Pages: 461

Quinones and Quinone Enzymes, Part A

  • Type: Book
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  • Published: 2004-05-01
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  • Publisher: Elsevier

Quinones are members of a class of aromatic compounds with two oxygen atoms bonded to the ring as carbonyl groups. This volume covers the role of quinines enzymes in cellular signalling and modulation of gene expression. *Coenzyme Q: Detection and Quinone Reductases *Plasma Membrane Quinone Reductases *Quinones, Cellular Signaling, and Modulation of Gene Expression

The Elms
  • Language: en
  • Pages: 386

The Elms

Elms occur, both naturally and cultivated, throughout much of the temperate world. Because of their high tolerance to extreme growing conditions and their widespread distribution, elms have been widely planted in cities, towns and rural areas throughout North America and northern Europe. As such, their current demise due to several pandemics of Dutch elm disease has spurred a huge body of research on breeding for disease resistance, conservation and systematics. The Elms: Breeding, Conservation and Disease Management provides the current state of knowledge in these areas and is an important reference work for pathologists, breeders, taxonomists, and arborists.

Women’s Health and Menopause
  • Language: en
  • Pages: 444

Women’s Health and Menopause

The 4th International Symposium on Women's Health and Menopause, organized by the Giovanni Lorenzini Medical Foundation (Milan, Italy and Houston, Texas) focused on the new strategies to improve the quality of life of post-menopausal women. This volume illustrates the findings of this conference and includes information on the age-related degenerative processes occurring after menopause including cardiovascular disease, cancer, fractures and dementia.

Official Gazette of the United States Patent and Trademark Office
  • Language: en
  • Pages: 904

Official Gazette of the United States Patent and Trademark Office

  • Type: Book
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  • Published: 1995
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  • Publisher: Unknown

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