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Gizi Molekuler merupakan cabang ilmu yang mempelajari tentang interaksi antara zat gizi dan berbagai molekul intraseluler dan ekstraseluler. Cabang ilmu ini muncul sebagai bidang baru dalam ilmu zat gizi dan merupakan salah satu bidang yang berkembang paling pesat bersamaan dengan kemajuan dalam dunia Biologi Molekuler yang dengan lebih nyata mampu menjelaskan respons organisme terhadap zat gizi pada tingkat molekuler, di antaranya: ekspresi gen, sinyal transduksi, dan juga modifikasi protein. Terdapat 14 Bab dalam buku ini. Pada Bab 1 diuraikan mengenai Pengantar Gizi Molekuler yang berisi penjelasan pengertian Gizi Molekuler, variasi genetik terkait diet, beserta contoh kasus evolusi varia...
Completely revised new edition of the definitive reference on disorders of hemoglobin.
Experienced and authoritative experts review the most important innovations and their biotechnological applications. An interdisciplinary view that examines the area from molecular biology, genome-, transcriptome- and proteome-wide perspectives, and looks at the ecological aspects and systems biology approaches.
This second edition provides new and updated methods and techniques for identification of drug target, binding sites prediction, high- throughput virtual screening, lead discovery and optimization, conformational sampling, prediction of pharmacokinetic properties using computer-based methodologies. Chapters also focus on the application of the latest artificial intelligence technologies for computer aided drug discovery. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary methods, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Computational Drug Discovery and Design, Second Edition aims to effectively utilize computational methodologies in discovery and design of novel drugs.
This book focuses on uterine endometrial function and receptivity from multiple perspectives. The chapters cover a variety of topics including the role of estrogen and progesterone, animal models, parameters for assessing endometrial receptivity, the mechanism of angiogenesis, epigenetic regulation, and stem/progenitor cells. Despite nearly 35 years of experience with in vitro fertilization, the rate of successful implantations remains low. Abnormal endometrial receptivity has been proposed as one of the factors contributing to reduced reproductive potential in women, but our understanding of it is limited. Endometrial receptivity results from an orchestrated interplay between the embryo and the maternal endometrium, and the receptive status, known as the window of implantation, is reached only briefly in the mid-luteal phase. This book provides a comprehensive overview of the latest advances in endometrial function and paves the way for innovative treatments and drug development for infertility. This work will appeal to a wide readership, from researchers on endometrial function and assisted reproductive technology (ART) to clinicians and technicians in the field of gynecology.
The origin and development of the oil palm industry. The botany of the oil palm. The climates and soils of the oil palm regions. Factors affecting growth, flowering and yield. Oil palm selection and breeding. Germination and the preparation and storage of seed. The raising of nursery seedlings. The preparation of land for oil palm plantations. The establishment of oil palms in the field. The care and maintenance of a plantation. The nutrition of the oil palm. Mixed cropping, rearing livestock among oil palms and tapping for wine. Diseases and pests of the oil palm. The products of the oil palm and their extraction.
Given the centrality of protein to many biological process, this book makes a significant contribution to the fields of healthcare and nutrition. Its chapters consider topics such as protein-protein and protein-ligand docking, and the protein engineering of enzymes involved in bioplastic metabolism. One contribution gives an overview of the In Vitro Virus (IVV) analytic method, while another shows how cutting-edge techniques in protein engineering advance our knowledge in the field of palaeontology. The book also includes a review of classic and alternative strategies when using yeasts in research, with a focus on Pichia pastoris as a host. Finally, there are two contributions on chromatography: one on the method itself, and another on its use to identify HMGB1-binding components.