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Development of Novel Anti-HIV Pyrimidobenzothiazine Derivatives
  • Language: en
  • Pages: 157

Development of Novel Anti-HIV Pyrimidobenzothiazine Derivatives

The author successfully developed novel anti-HIV PD 404182 derivatives that exhibited submicromolar inhibitory activity against both HIV-1 and HIV-2. His thesis is in three parts. The first part expounds efficient methods for the synthesis of tricyclic heterocycles related to PD 404182 based on the sp2-carbonāˆ’heteroatom bond formations. Starting from arene or haloarene, C-O, C-N, or C-S bonds were formed by simply changing the reactants. These synthetic methods provide powerful approaches for the divergent preparation of pyrimido-benzoxazine, -quinazoline, or -benzothiazine derivatives. The second part explains SAR studies of PD 404182 for the development of anti-HIV agents. Through optimi...

Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds
  • Language: en
  • Pages: 115

Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds

The author has developed novel methodologies for highly efficient construction of functionalized heterocycles by palladium-catalyzed domino/cascade cyclization of allenes and related compounds containing appropriate nucleophilic group(s). Based on these methodologies, enantioselective total syntheses of bioactive natural products, pachastrissamine (26% overall yield in seven steps), lysergic acid (4.0% overall yield in fifteen steps), lysergol (3.6% overall yield in fifteen steps) and isolysergol (8.2% overall yield in eleven steps) have been achieved. These are more facile synthetic route than those previously reported. These findings would contribute to the development of efficient synthetic methods for biologically active compounds containing a complex structure.

Bulletin of the Chemical Society of Japan
  • Language: en
  • Pages: 676

Bulletin of the Chemical Society of Japan

  • Type: Book
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  • Published: 2009
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  • Publisher: Unknown

None

Communication in Personal Relationships Across Cultures
  • Language: en
  • Pages: 282

Communication in Personal Relationships Across Cultures

  • Type: Book
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  • Published: 1996-08-07
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  • Publisher: SAGE

Communication in Personal Relationships Across Cultures examines the communication practices of non-Western cultures. The international cast of contributors assembled here leaves behind the biases typical of most research and theorizing done in this area of communication and enables the reader to develop a thorough understanding of how people communicate in non-Western societies. Chapters focus on communication practices in China, Japan, Korea, Mexico, Brazil, Iran, Africa, and totalitarian societies. Through both emic and etic approaches, this groundbreaking volume explores how members of a culture understand their own communication, and compares the similarities and differences of specific aspects of communication across cultures. --From publisher's description.

Index of Patents Issued from the United States Patent and Trademark Office
  • Language: en
  • Pages: 1948

Index of Patents Issued from the United States Patent and Trademark Office

  • Type: Book
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  • Published: 1993
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  • Publisher: Unknown

None

Official Gazette of the United States Patent and Trademark Office
  • Language: en
  • Pages: 756

Official Gazette of the United States Patent and Trademark Office

  • Type: Book
  • -
  • Published: 2002
  • -
  • Publisher: Unknown

None

The Toho Studios Story
  • Language: en
  • Pages: 556

The Toho Studios Story

Since its inception in 1933, Toho Co., Ltd., Japan's most famous movie production company and distributor, has produced and/or distributed some of the most notable films ever to come out of Asia, including Seven Samurai, Godzilla, When a Woman Ascends the Stairs, Kwaidan, Woman in the Dunes, Ran, Shall We Dance?, Ringu, and Spirited Away. While the western world often defines Toho by its iconic classics, which include the Godzilla franchise and many of the greatest films of the legendary director Akira Kurosawa and actor Toshiro Mifune, these pictures represent but a tiny fraction of Toho's rich history. The Toho Studios Story: A History and Complete Filmography provides a complete picture o...

Index of Patents Issued from the United States Patent Office
  • Language: en
  • Pages: 2300

Index of Patents Issued from the United States Patent Office

  • Type: Book
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  • Published: 1975
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  • Publisher: Unknown

None

Commencement
  • Language: en
  • Pages: 260

Commencement

  • Type: Book
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  • Published: 1951
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  • Publisher: Unknown

None

Register of the University of California
  • Language: en
  • Pages: 1098

Register of the University of California

  • Type: Book
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  • Published: 1952
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  • Publisher: Unknown

None