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Clinical Bioinformatics
In Clinical Bioinformatics, Second Edition, leading experts in the field provide a series of articles focusing on software applications used to translate information into outcomes of clinical relevance. Recent developments in omics, such as increasingly sophisticated analytic platforms allowing changes in diagnostic strategies from the traditional focus on single or small number of analytes to what might be possible when large numbers or all analytes are measured, are now impacting patient care. Covering such topics as gene discovery, gene function (microarrays), DNA sequencing, online approaches and resources, and informatics in clinical practice, this volume concisely yet thoroughly explores this cutting-edge subject. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Clinical Bioinformatics, Second Edition serves as an ideal guide for scientists and health professionals working in genetics and genomics.
Biological Mass Spectrometry
Describes and integrates the techniques of many advances in both chromatographic and mass spectrometric technologies. This book also covers various biophysical applications, such as H/D exchange for study of conformations, protein-protein and protein-metal and ligand interactions. It also describes atto-to-zepto-mole quantitation of 14C and 3H.
The Gale Encyclopedia of Medicine
Contains articles that provide medical information about a wide variety of common diseases, disorders, tests, and treatments; arranged alphabetically from T-to-Z; and includes cross-references, definitions of terms, lists of resources, and a comprehensive general index.
Medieval Women and Urban Justice
This is the first in-depth, comparative study of women's access to justice in medieval English towns. It compares the records of Nottingham, Chester and Winchester and a wide range of legal actions to highlight the variable nature of women's legal status in actions that arose from the complex, messy ties of everyday life.
The Wrong Side of the Bed
The Wrong Side of the Bed tells the story of George who wakes up on the wrong side of the bed and makes everyone’s life miserable until Mom take control and sends him back for a nap. The book is written in poetic format and is excellent for beginning readers as it repeats key words while introducing new words in every line.
Bog bodies
This electronic version has been made available under a Creative Commons (BY-NC-ND) open access license. The ‘bog bodies’ of north-western Europe have captured the imaginations of poets and archaeologists alike, allowing us to come face-to-face with individuals from the past. Their exceptional preservation permits us to examine minute details of their lives and deaths, making us reflect poignantly on our own mortality. But, as this book argues, the bodies must be resituated within a turbulent world of endemic violence and change. Reinterpreting the latest continental research and new discoveries, and featuring a ground-breaking ‘cold case’ forensic study of Worsley Man, Manchester Museum’s ‘bog head’, it brings the bogs to life through both natural history and folklore, revealing them as places that were rich and fertile yet dangerous. The book also argues that these remains do not just pose practical conservation problems but also philosophical dilemmas, compounded by the critical debate on if – and how – they should be displayed.
Leprosy and identity in the Middle Ages
For the first time, this volume explores the identities of leprosy sufferers and other people affected by the disease in medieval Europe. The chapters, including contributions by leading voices such as Luke Demaitre, Carole Rawcliffe and Charlotte Roberts, challenge the view that people with leprosy were uniformly excluded and stigmatised. Instead, they reveal the complexity of responses to this disease and the fine line between segregation and integration. Ranging across disciplines, from history to bioarchaeology, Leprosy and identity in the Middle Ages encompasses post-medieval perspectives as well as the attitudes and responses of contemporaries. Subjects include hospital care, diet, sanctity, miraculous healing, diagnosis, iconography and public health regulation. This richly illustrated collection presents previously unpublished archival and material sources from England to the Mediterranean.
Eradicating Deafness?
How did American geneticists go from fearing the dysgenic effects of deaf intermarriage to considering modern biotechnology a threat for Deaf culture? This book provides insight into changing ideas of what deafness is, what science and medicine should achieve, and to the transformative effect of exchange between scientists and deaf communities.
