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The Immunological Implications of the Hygiene Hypothesis
  • Language: en
  • Pages: 139

The Immunological Implications of the Hygiene Hypothesis

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The Hygiene Hypothesis and Darwinian Medicine
  • Language: en
  • Pages: 312

The Hygiene Hypothesis and Darwinian Medicine

Man has moved rapidly from the hunter-gatherer environment to the living conditions of industrialised countries. The hygiene hypothesis suggests that the resulting reduced exposure to micro-organisms has led to disordered regulation of the immune system, and hence to increases in certain chronic inflammatory disorders, like allergic disorders, autoimmunity, inflammatory bowel disease, atherosclerosis, depression, some cancers and perhaps Alzheimer and Parkinson. This book discusses the evidence for and against in the context of Darwinian medicine, which uses knowledge of evolution to cast light on human diseases. The approach is interdisciplinary, looking at man’s microbiological history, at the biology of the effects of microorganisms on the immune system, and at the implications for chronic inflammatory disorders in multiple organ systems. Finally, the authors describe progress in the exploitation of microorganisms or their components as novel prophylactics and treatments.

Microbial Host-interaction
  • Language: en
  • Pages: 278

Microbial Host-interaction

Most indigenous microbes occur in the intestinal tract, and their interactions with the host are largely unknown. Current understanding of host-microbe interactions links early microbial contact to the origin of disease, a theory that has its roots in the hygiene hypothesis. Modern life style appears to deprive the infant of conditions that provide adequate anti-inflammatory or tolerogenic stimuli upon antigen encounter. Thus, maturational signals from the environment and the diet are insufficient to adequately shape the immune system. This publication deals with the relationship between the gut microbiota as well as altered pattern of early microbial contact and the origin of human disease. New aspects of the original hygiene hypothesis are discussed in relation to disorders spanning from allergy and autoimmunity to obesity.The results presented suggest that all these disorders may be linked to aberrant antigen absorption and immune responses associated with dysfunction of mucosal defense. Researchers, clinicians and students interested in the interaction of the host with indigenous gut bacteria and the consequences for human health will find this publication of utmost interest.

Local Immunotherapy in Allergy
  • Language: en
  • Pages: 153

Local Immunotherapy in Allergy

The incidence of allergies is increasing worldwide. Beside the well-established symptomatic treatments and subcutaneous immunotherapies, formerly known as de- or hyposensitization, a new form of treatment, local immunotherapy, has been developed in recent years. Local immunotherapy, though still controversially discussed, promises to be a curative, noninvasive, and easily applicable treatment for allergies. This volume summarizes the most current information on local immuntherapy compiled by internationally renowned specialists. In the methodology section, general aspects of local immunotherapy are presented including its history, allergen resorption and biodistribution, mechanisms of oral t...

Travel Medicine, An Issue of Infectious Disease Clinics
  • Language: en
  • Pages: 281

Travel Medicine, An Issue of Infectious Disease Clinics

It is extremely important that physicians be aware of the wide spectrum of tropical, infectious and parasitic diseases their patients may have been exposed to while traveling abroad. This volume of the ID Clinics is edited by 3 internationally renowned infectious disease physicians and provides an authoritative and comprehensive treatise on Travel Medicine.

Advances in Applied Microbiology
  • Language: en
  • Pages: 425

Advances in Applied Microbiology

  • Type: Book
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  • Published: 2005-01-06
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  • Publisher: Elsevier

Advances in Applied Microbiology offers intensive reviews of the latest techniques and discoveries in this rapidly moving field. The editors are recognized experts and the format is comprehensive and instructive. This volume contains 12 comprehensive reviews, including: Uses of Trichoderma spp. to alleviate or remediate soil and water pollution; Lincosamides, chemical structure, biosynthesis, mechanism of action, resistance and applications; Polysaccharide breakdown by anaerobic microogranisms inhabiting the mammalian gut; and Novel aspects of signaling in Streptomyces development.* This series has been in constant publication since 1959* An ISI impact factor of 1.0 in 2002* This volume contains 12 comprehensive reviews of current research in applied microbiology

Travel Medicine
  • Language: en
  • Pages: 569

Travel Medicine

Travel Medicine, 3rd Edition, by Dr. Jay S. Keystone, Dr. Phyllis E. Kozarsky, Dr. David O. Freedman, Dr. Hans D. Nothdruft, and Dr. Bradley A. Connor, prepares you and your patients for any travel-related illness they may encounter. Consult this one-stop resource for best practices on everything from immunizations and pre-travel advice to essential post-travel screening. From domestic cruises to far-flung destinations, this highly regarded guide offers a wealth of practical guidance on all aspects of travel medicine. "This is an excellent reference source that contains words of wisdom which covers an area of medicine which can sometimes get lost on the radar screen". Reviewed by: Dr Harry B...

Emerging Infectious Diseases
  • Language: en
  • Pages: 1124

Emerging Infectious Diseases

  • Type: Book
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  • Published: 2012
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  • Publisher: Unknown

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Advances in Applied Microbiology
  • Language: en
  • Pages: 163

Advances in Applied Microbiology

Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology. The series contains comprehensive reviews of the most current research in applied microbiology. Recent areas covered include bacterial diversity in the human gut, protozoan grazing of freshwater biofilms, metals in yeast fermentation processes and the interpretation of host-pathogen dialogue through microarrays. Eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndrome. Impact factor for 2009: 1.860. Contributions from leading authorities Informs and updates on all the latest developments in the field Reference and guide for scientists and specialists involved in advancements in applied microbiology

Advances in Applied Microbiology
  • Language: en
  • Pages: 174

Advances in Applied Microbiology

Annotation Published since 1959, 'Advances in Applied Microbiology' offers comprehensive reviews of the latest techniques and discoveries in this rapidly moving field.