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Metabolome Analysis
Providing information on the main approaches for the analysis of metabolites, this textbook: Covers basic methodologies in sample preparation and separation techniques, as well as the most recent techniques of mass spectrometry. Differentiates between primary and secondary metabolites. Includes four chapters discussing successful metabolome studies of different organisms. Highlights the analytical challenges of studying metabolites. Illustrates applications of metabolome analysis through the use of case studies.
Concepts in Plant Metabolomics
Like genomics, which defines genes in a genome irrespective of functionality, metabolomics profiles all metabolites in a biological sample irrespective of the chemical and physical properties of these molecules. Metabolomics can potentially define cellular processes by providing a measure of the ultimate phenotype of an organism, characterized by the collage of small molecules whose levels of accumulation is altered in response to genetic and environmentally induced changes in gene expression.
Metabolomics in Crop Research – Current and Emerging Methodologies
The plant metabolome is highly complex, being composed of over 200,000 metabolites. The characterization of these small molecules has been crucial to study plant growth and development as well as their response to environmental changes. The potential of metabolomics in plant research, particularly if applied to crop plants, is also extremely valuable in the discovery of biomarkers and in the improvement of crop yield and quality. This Frontiers Research Topic addresses many applications of metabolomics to crop research, based on different analytical platforms, including mass spectrometry, and nuclear magnetic resonance. It comprises 13 articles from 109 authors that show the importance and the contribution of metabolomics in the analysis of crop’s traceability and genetic variation, in the study of fruit development, and in the understanding of the plant’s response to the environment and to different biotic and abiotic stresses.
Rice Functional Genomics
Rice has been chosen as a model cereal for functional genomics because of its well understood genetics. In addition, there is great similarities among all the cereals and grasses: any understanding of rice genes is directly applicable to the genes of other cereals. This book details rice functional genomics. It takes a multi-pronged genome-wide approach using structural similarities, expression profiles, and mutant phenotypes. Coverage includes the current status of genome sequencing and annotation, various tools, and resources being developed worldwide.
Metabolomics
Metabolomics is a rapidly emerging field in life sciences, which aims to identify and quantify metabolites in a biological system. Analytical chemistry is combined with sophisticated informatics and statistics tools to determine and understand metabolic changes upon genetic or environmental perturbations. Together with other 'omics analyses, such as genomics and proteomics, metabolomics plays an important role in functional genomics and systems biology studies in any biological science. This book will provide the reader with summaries of the state-of-the-art of technologies and methodologies, especially in the data analysis and interpretation approaches, as well as give insights into exciting applications of metabolomics in human health studies, safety assessments, and plant and microbial research.
Science
A weekly record of scientific progress.
Personalized Medicine in the Making
This book offers a multidisciplinary look at the much-debated concept of “personalized medicine”. By combining a humanistic and a scientific approach, the book builds up a multidimensional way to understand the limits and potentialities of a personalized approach in medicine and healthcare. The book reflects on personalized medicine and complex diseases, the relationship between personalized medicine and the new bio-technologies, personalized medicine and personalized nutrition, and on some ethical, political, economic, and social implications of personalized medicine. This volume is of interest to researchers from several disciplines including philosophy, bio-medicine, and the social sciences. Chapter 16, “The Impact of Fantasy” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
The Handbook of Plant Metabolomics
This is the newest title in the successful Molecular Plant Biology Handbook Series. Just like the other titles in the series this new book presents an excellent overview of different approaches and techniques in Metabolomics. Contributors are either from ivy-league research institutions or from companies developing new technologies in this dynamic and fast-growing field. With its approach to introduce current techniques in plant metabolomics to a wider audience and with many labs and companies considering to introduce metabolomics for their research, the title meets a growing market. The Kahl books are in addition a trusted brand for the plant science community and have always sold above expectations.
