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Multiscale Cancer Modeling
Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of dat
Interfacial Fluid Dynamics and Transport Processes
The present set of lectures and tutorial reviews deals with various topical aspects related to instabilities of interfacial processes and driven flows from both the theoretical and experimental point of views. New research has been spurred by demands for many applications in material sciences (melting, solidification, electro deposition), biomedical engineering and processing in microgravity environments. This book is intended as both a modern source of reference for researchers in the field as well as an introduction to postgraduate students and non-specialists from related areas.
Nanomedicine
This book offers a fundamental and comprehensive overview of nanomedicine from a systems engineering perspective, making it the first book in the field of quantitative nanomedicine based on systems theory. The book starts by introducing the concept of nanomedicine and provides basic mathematical modeling techniques that can be used to model nanoscale biomedical and biological systems. It then demonstrates how this idea can be used to model and analyze the central dogma of molecular biology, tumor growth and the immune system. Broad applications of the idea are further illustrated by Bayesian networks, multiscale and multiparadigm modeling and AFM engineering.
Multiscale Computer Modeling in Biomechanics and Biomedical Engineering
This book reviews the state-of-the-art in multiscale computer modeling, in terms of both accomplishments and challenges. The information in the book is particularly useful for biomedical engineers, medical physicists and researchers in systems biology, mathematical biology, micro-biomechanics and biomaterials who are interested in how to bridge between traditional biomedical engineering work at the organ and tissue scales, and the newer arenas of cellular and molecular bioengineering.
Selected Topics in Cancer Modeling
This collection of selected chapters offers a comprehensive overview of state-of-the-art mathematical methods and tools for modeling and analyzing cancer phenomena. Topics covered include stochastic evolutionary models of cancer initiation and progression, tumor cords and their response to anticancer agents, and immune competition in tumor progression and prevention. The complexity of modeling living matter requires the development of new mathematical methods and ideas. This volume, written by first-rate researchers in the field of mathematical biology, is one of the first steps in that direction.
Computational Biology
This volume covers techniques in computational biology and their applications in oncology. It details advanced statistical methods, heuristic algorithms, cluster analysis, data modeling, and image and pattern analysis applied to cancer research.
Materials Characterisation VII
Containing papers presented at the Seventh International Conference on Materials Characterisation, this book presents the latest advances in a rapidly developing field that requires the application of a combination of numerical and experimental methods. The work has been contributed by researchers who use computational methods, those who perform experiments, and those who combine both. Materials characterisation is important to ensuring that new products meet the needs of industry and consumers. The accurate characterisation of the physical and chemical properties of the materials requires the application of both experimental techniques and computer simulation methods. The wide range of materials now available, from metals to polymers and semiconductors to composites, necessitates a variety of experimental techniques and numerical methods. The papers in the book examine various combinations of techniques. The papers cover such topics as: Mechanical Characterisation and Testing; Micro and Macro Materials Characterisation; Cementitious Materials; Advances in Composites; Semiconductor Materials Characterisation; Computational Models and Experiments; Corrosion Problems.
Non-Local Cell Adhesion Models
This monograph considers the mathematical modeling of cellular adhesion, a key interaction force in cell biology. While deeply grounded in the biological application of cell adhesion and tissue formation, this monograph focuses on the mathematical analysis of non-local adhesion models. The novel aspect is the non-local term (an integral operator), which accounts for forces generated by long ranged cell interactions. The analysis of non-local models has started only recently, and it has become a vibrant area of applied mathematics. This monograph contributes a systematic analysis of steady states and their bifurcation structure, combining global bifurcation results pioneered by Rabinowitz, equivariant bifurcation theory, and the symmetries of the non-local term. These methods allow readers to analyze and understand cell adhesion on a deep level.
Interface Problems and Methods in Biological and Physical Flows
This volume showcases lecture notes collected from tutorials presented at the Workshop on Moving Interface Problems and Applications in Fluid Dynamics that was held between January 8 and March 31, 2007 at the Institute for Mathematical Sciences, National University of Singapore. As part of the program, these tutorials were conducted by specialists within their respective areas such as Robert Dillon, Zhilin Li, John Lowengrub, Frank Lu and Gretar Tryggvason.The topics in the program encompass modeling and simulations of biological flow coupled to deformable tissue/elastic structure, shock wave and bubble dynamics and various applications like biological treatments with experimental verification, multi-medium flow or multiphase flow and various applications including cavitation/supercavitation, detonation problems, Newtonian and non-Newtonian fluid, and many other areas.This volume stand to benefit graduate students and researchers keen in the field of interfacial flows for application to physical and biological systems. Even beginners will find this volume a very useful starting point with many relevant references applicable.
Micro Process Engineering, 3 Volume Set
This three-volume handbook provides an overview of the key aspects of micro process engineering. Volume 1 covers the fundamentals, operations and catalysts, volume 2 examines devices, reactions and applications, with volume 3 rounding off the trilogy with system, process and plant engineering. Fluid dynamics, mixing, heat/mass transfer, purification and separation microstructured devices and microstructured reactors are explained in the first volume. Volume 2 segments microreactor design, fabrication and assembly, bulk and fine chemistry, polymerisation, fuel processing and functional materials into understandable parts. The final volume of the handbook addresses microreactor systems design and scale-up, sensing, analysis and control, chemical process engineering, economic and eco-efficiency analyses as well as microreactor plant case studies in one book. Together, this 3-volume handbook explains the science behind micro process engineering to the scale-up and their real life industrial applications.
