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Molecular basis of gradual adaptation of body systems in stressful conditions is a great mystery of biology. Such an adaptation not only increases tolerance of the body to that given stress but also to other challenges. An understanding of this cross protection needs to be exploited to improve patient care. The book includes 25 chapters describing molecular, subcellular and organ biology. Although for an easy reading the information has been grouped under the sub-headings: Adaptation to Cardiovascular Stresses, Adaptation to Neurohumoral Stresses, Adaptation to Other Stresses, the book represents a common continuum of adaptations. The therapeutic value of the understanding of the science of adaptation has also been described in several chapters. Examples of cross adaptations are also provided, where repeated exposure to one stimulus may have applications in the treatment and prophylaxis of different diseases.The present book will be of great interest to all biologists, physiologists, pharmacologiss and physicians interested in the application of the biology of adaptation in the improvement of health.
Published in 1991: This book explores the possibilities of protecting the heart against stress and ischemia through adaptation to intermittent hypoxia or to mild, nondamaging stress exposure. These possibilities are based on studies that show an increase in the potency and efficiency of stress-limiting systems when subjected to repeated stress actions, adaptation to high altitude hypoxia, or adaptation to increased physical loads. Any stress reaction is coupled with an activation of central and local stress-limiting systems, such as GABA-ergic, opioidergic, and serotonergic systems in the brain, as well as antioxidants, prostaglandins, and adenosine in executory organs. The book also presents the use of metabolites of stress-limiting systems rather than adaptation as a means to prevent cardiac arrythmias. It also discusses genetically determined deficiencies of stress-limiting systems and their role in the etiology of stress-induced diseases. Cardiologists and researchers studying stress and its effect on cardiovascular systems will find this book extremely useful.
All scientific claims indicate one result that food and nutrition is an integral part of medicine while medicine can not show its curing potential without a correct and complementary food and nutrition. A blood thinning (anticoagulant) drug when combined with too much blood thinning food consumption can increase the risk of internal bleeding risk and may be fatal. Bergamottin in grapefruit can inhibit the activity of liver enzymes and can cause the accumulation of radio and chemotherapeutic agents in blood which can increase the side effects of such anti-carcinogen treatments. Similarly, fibers which are introduced as healthy food components with their weight loosing and cancer protecting ef...
This book contains best selected research papers presented at ICTCS 2022: Seventh International Conference on Information and Communication Technology for Competitive Strategies. The conference will be held in Chandigarh, India, during December 9–10, 2022. The book covers state-of-the-art as well as emerging topics pertaining to ICT and effective strategies for its implementation for engineering and managerial applications. This book contains papers mainly focused on ICT for computation, algorithms and data analytics and IT security. The work is presented in two volumes.
Just what does it take to be a stratonaut, soaring to higher and higher altitudes of Earth's atmosphere? Brave men and women have reached extreme heights in balloons, aircraft and rocket ships over the past two centuries, from the first untethered balloon flight to the first flights in the newly defined stratosphere, through to the present flights that continue to set new records. This book defines the altitudes related to the stratosphere, how it changes with latitude and the effects on ascending aviators. Also described is how over time technology enabled aircraft and balloons to achieve higher altitudes. The book shows the clear influence of the military on designs that initially focused ...
It has become amply clear that all live forms on Earth are the products of the constituent genes expressed under the influence of continuously changing natural environment. By the same token, gene expression is known to be modified by our (or by the modern) environment inclusive of factors such as gravity, altitude, temperature, atmospheric pressure and air quality, physical conditioning as well as nutrition and/or lifestyle. Life would not survive without recruiting endogenous adaptive mechanisms responsive to challenging environmnetal factors, Biology of adaptation as well as application of this knowledge has been discussed in both health and disease conditions such as cardiac ischemia and cardiomyopathies, stroke, dementia, Alzheimer's, cancer, metal toxicity, etc. The book will be of great interest to experimental biologists and health professionals dealing with benefits and failures of physiological and pathophysiological adaptations. It will also serve as an important source of information for young scientists, postdocs and students.