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Self-Organization
According to its definition, Synergetics is concerned with systems that produce macroscopic spatial, temporal, or functional structures. Autowaves are·a specific, yet very important, case of spatio-temporal structures. The term "autowave" was coined in the Soviet Union in analogy to the term "auto-oscillator". This is - perhaps too literal - translation of the Russian word "avto-ostsillyatory" (= self oscillator) which in its proper translation means "self-sustained oscillator". These are oscillators, e. g. , clocks, whose internal energy dissipation is compensa ted by a (more or less) continuous power input. Simi larly, the term "autowaves" de notes propagation effects - including waves - ...
Foundations of Synergetics I
This book gives an introduction to the mathematical theory of cooperative behavior in active systems of various origins, both natural and artificial. It is based on a lecture course in synergetics which I held for almost ten years at the University of Moscow. The first volume deals mainly with the problems of pattern formation and the properties of self-organized regular patterns in distributed active systems. It also contains a discussion of distributed analog information processing which is based on the cooperative dynamics of active systems. The second volume is devoted to the stochastic aspects of self-organization and the properties of self-established chaos. I have tried to avoid delvi...
Foundations of Synergetics II
The second edition of this volume has been extensively revised. A different version of Chap. 7, reflecting recent significant progress in understanding of spatiotempo ral chaos, is now provided. Much new material has been included in the sections dealing with intermittency in birth-death models and noise-induced phase transi tions. A new section on control of chaotic behavior has been added to Chap. 6. The subtitle of the volume has been changed to better reflect its contents. We acknowledge stimulating discussions with H. Haken and E. Scholl and are grateful to our colleagues M. Bar, D. Battogtokh, M. Eiswirth, M. Hildebrand, K. Krischer, and V. Tereshko for their comments and assistance. W...
Complex Structure and Dynamics of the Heart
This award-winning thesis investigates the mechanisms underlying cardiac arrhythmia development and termination from an entirely new perspective. By viewing the heart as a complex system, the author uses theoretical tools from nonlinear dynamics combined with numerical simulations and experiments to achieve insights into the relationship between its structure and dynamics, thereby paving the way towards innovative low-energy defibrillation strategies. The work tackles, among other things: the effect of substrate heterogeneity on the spatial-temporal dynamics of cardiac arrhythmias and ways in which weak pulsed electric fields can be used to control these dynamics in heterogeneous cardiac tissue. The long-term vision of this research is to replace the current strategy of applying painful and sometimes tissue damaging electric shock – currently the only reliable way to terminate life-threatening fibrillation – by a more subtle but equally effective intervention. The book maps out a number of promising research directions for biophysicists and medical researchers working on the origins and treatment of cardiac arrhythmias.
Cardiac Bioelectric Therapy
Pacing and defibrillation have become the leading therapeutic treatments of heart rhythm disorders, including bradycardia and tachycardia. The success of these therapies is largely due to centuries of scientific inquiry into the fundamental mechanisms of bioelectric phenomena in the heart. History of successful development of bioelectric therapies includes development of experimental and theoretical methodologies, novel bioengineering approaches, and state-of-the-art clinical implantable device therapies. The purpose of this book is to present a uniform thematic collection of reviews written by the leading basic and applied scientists working in basic bioengineering research laboratories, wh...
The Geometry of Biological Time
Dealing with dynamics of processes that repeat themselves regularly, this revised and updated edition extends the thread from 1980 to the present day, concentrating on areas of interest where there will be much activity in the future. This involves going through spatial biochemical, electrophysiological, and organismic dynamical systems and patterns that were discovered by pursuing the theme of phase singularities introduced in the original book. In particular the work on excitability in cell membranes will be thoroughly updated as will the references throughout the book.
Nonlinear Wave Processes in Excitable Media
Proceedings of a NATO ARW held in Leeds, UK, September 11-15, 1989
Dissipative Structures in Transport Processes and Combustion
Any description of the workings of nature by means of measurements and ob servations is beset with the problem of how to cope with an immense amount of information. In physics, it is an established approach to derive basic equations which then serve as cornerstones of what is called a theory of the phenomena. This derivation is based on certain characteristics of the phenomena, the refine ment of which results from a reduction of the amount of empirical information, with the reduction leading to an enhancement of the very characteristics that are sought for in the otherwise seemingly amorphous wealth of data. If physics is mainly concerned with the derivation of equations, lately there has e...
An Introduction to Mathematical Modeling in Physiology, Cell Biology, and Immunology
In many respects, biology is the new frontier for applied mathematicians. This book demonstrates the important role mathematics plays in the study of some biological problems. It introduces mathematicians to the biological sciences and provides enough mathematics for bioscientists to appreciate the utility of the modelling approach. The book presents a number of diverse topics, such as neurophysiology, cell biology, immunology, and human genetics. It examines how research is done,what mathematics is used, what the outstanding questions are, and how to enter the field. Also given is a brief historical survey of each topic, putting current research into perspective. The book is suitable for mathematicians and biologists interested in mathematical methods in biology.
