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Biology and therapeutic potential of brown adipose tissue
Brown adipose tissue (BAT) has long been recognized as a key thermogenic tissue in eutherian mammals. Brown fat cells contain large numbers of highly specialized mitochondria that oxidize fat and carbohydrate to produce heat. This metabolic inefficiency is due to the presence of Ucp1 in the inner mitochondrial membrane of brown fat cells which dissociates the electrochemical gradient from ATP production. BAT presumably evolved to protect animals against hypothermia in response to cold exposure. However, energy expended by BAT has the added benefit of counteracting obesity and associated metabolic disease, at least in rodents. A very large number of studies have consistently shown that mice c...
Osteoporosis in Men
Since the publication of the first edition, the U.S. Surgeon General released the first-ever report on bone health and osteoporosis in October 2004. This report focuses even more attention on the devastating impact osteoporosis has on millions of lives. According to the National Osteoporosis Foundation, 2 million American men have osteoporosis, and another 12 million are at risk for this disease. Yet despite the large number of men affected, the lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated. It is estimated that one-fifth to one-third of all hip fractures occur in men. This second edition brings on board John Bil...
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Pediatric Orthopedic Imaging
This book is an indispensable reference for pediatric and musculoskeletal radiologists, as well as orthopedic surgeons. It offers in depth analysis of pediatric orthopedic imaging, covering normal and aberrant development as well as both common and unusual pediatric disorders. Chapters on the spine, shoulder, elbow, hand and wrist, hip and pelvis, lower extremity, and foot and ankle address site-specific congenital and acquired lesions. Subsequent chapters cover generalized orthopedic diseases such as neurofibromatosis and osteogenesis imperfecta, infectious processes, neuromuscular diseases, musculoskeletal tumors, trauma, and orthopedic procedures. The chapters review associated epidemiology, clinical presentation and evolution, treatment, and differential diagnoses, with in-depht analysis of imaging characteristics. With more than 1800 images, high-quality MRI, CT, and US examples complement the radiographs of a broad variety of musculoskeletal disorders.
Pediatric Bone
Pediatric Bone is the first book to be published to deal exclusively with the biology and diseases of bone as they affect children. Rapid advances have been made in our understanding of the mechanisms and factors controlling the growth and development of bone, and these are discussed in detail in this book. Further, the various diseases of bone which are peculiar to children are highlighted and discussed in the light of our current knowledge with regard to the causation, clinical signs and treatment. The book is aimed to provide those clinicians interested in children's diseases and basic scientists with a comprehensive resource covering the various aspects of bone health and disease in childrenKey Features* Deals exclusively with bone development and diseases of children and each chapter written by an * Fully referenced providing an appendix of usually difficult to find information on the investigation of pediatric bone disease and reference values* Covers both the physiology of bone and mineral homeostasis in children and diseases in one book* Includes a CD-ROM of images
Nutritional Influences on Bone Health
Nutritional Influences on Bone Health presents a collection of papers from the 8th International Symposium on Nutritional Aspects of Osteoporosis, the primary forum for and only regular meeting exclusively devoted to the topic of nutritional influences on bone health. The outcome is a fusion of the most current and up-to-date research in this area. Key themes include the permeation of the Western diet across the globe, calcium, vitamin D and acid-base balance. Written by authorities on the impact of nutrition on bone health, Nutritional Influences on Bone Health brings the reader the emerging trends, new messages and the latest scientific data in the field, to inform future research and clinical practice. This comprehensive, well researched volume is an essential reference for professionals in the field of bone health and nutrition.
Hand Bone Age
In the past, determination of bone maturity relied on visual evaluation of skeletal development in the hand and wrist, most commonly using the Greulich and Pyle atlas. The Gilsanz and Ratib digital atlas takes advantage of digital imaging and provides a more effective and objective approach to assessment of skeletal maturity. The atlas integrates the key morphological features of ossification in the bones of the hand and wrist and provides idealized, sex- and age-specific images of skeletal development New to this revised second edition is a description and user manual for Bone Age for iPad®, iPhone® and iPod touch®, which can be purchased and used separately from this book. The App can be easily employed to calculate the deviation of the patient’s age from the normal range and to predict a possible growth delay. This easy-to-use atlas and the related App will be invaluable for radiologists, endocrinologists, and pediatricians and also relevant to forensic physicians.
Hand Bone Age
For decades, the determination of bone maturity has relied on a visual evaluation of skeletal development in the hand and wrist, most commonly using the Greulich and Pyle atlas. The Gilsanz and Ratib digital atlas takes advantage of the advent of digital imaging and provides a more effective and objective approach to skeletal maturity assessment. This atlas integrates the key morphological features of ossification in the bones of the hand and wrist and provides idealized, sex- and age-specific images of skeletal development. This computer-generated set of images should serve as a reasonable alternative to the reference books currently available.
Current Catalog
First multi-year cumulation covers six years: 1965-70.
