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Intelligent Computing and Networking
This book gathers high-quality peer-reviewed research papers presented at the International Conference on Intelligent Computing and Networking (IC-ICN 2021), organized by the Computer Department, Thakur College of Engineering and Technology, in Mumbai, Maharashtra, India, on February 26–27, 2021. The book includes innovative and novel papers in the areas of intelligent computing, artificial intelligence, machine learning, deep learning, fuzzy logic, natural language processing, human–machine interaction, big data mining, data science and mining, applications of intelligent systems in health ,care, finance, agriculture and manufacturing, high-performance computing, computer networking, sensor and wireless networks, Internet of Things (IoT), software-defined networks, cryptography, mobile computing, digital forensics, and blockchain technology.
Cancer Drug Resistance
Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene amplification in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin.
