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How hype, money, and bias can mislead the public into thinking that many worthless or unproven treatments are effective. Each week, people read about new and exciting cancer drugs. Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel—but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices ...
Why medicine adopts ineffective or harmful medical practices only to abandon them—sometimes too late. Medications such as Vioxx and procedures such as vertebroplasty for back pain are among the medical "advances" that turned out to be dangerous or useless. What Dr. Vinayak K. Prasad and Dr. Adam S. Cifu call medical reversal happens when doctors start using a medication, procedure, or diagnostic tool without a robust evidence base—and then stop using it when it is found not to help, or even to harm, patients. In Ending Medical Reversal, Drs. Prasad and Cifu narrate fascinating stories from every corner of medicine to explore why medical reversals occur, how they are harmful, and what can be done to avoid them. They explore the difference between medical innovations that improve care and those that only appear to be promising. They also outline a comprehensive plan to reform medical education, research funding and protocols, and the process for approving new drugs that will ensure that more of what gets done in doctors' offices and hospitals is truly effective.
Although research in curve shortening flow has been very active for nearly 20 years, the results of those efforts have remained scattered throughout the literature. For the first time, The Curve Shortening Problem collects and illuminates those results in a comprehensive, rigorous, and self-contained account of the fundamental results. The a
This book covers diverse themes, including institutions and efficiency, choice and values, law and economics, development and policy, and social and economic measurement. Written in honour of the distinguished economist Satish K. Jain, this compilation of essays should appeal not only to students and researchers of economic theory but also to those interested in the design and evaluation of institutions and policy.
In The Lost Art of Caring, Leighton E. Cluff, M.D., and Robert H. Binstock, Ph.D., bring together experts to address the importance of caring, the reasons why it has eroded, and measures that can strengthen caring as provided by health professionals, families, communities, and society.
The US prescription drug business is a $500 billion industry whose rising prices carry profound consequences for patients, caregivers, employers and taxpayers across the nation. In the United States, average prices of leading brand-name drugs are two to four times higher than prices charged in other wealthy countries, raising questions as to what Americans are getting for the extra expense. On the other hand, healthy industry returns have arguably fueled life-saving innovation. With the advent of ever more targeted and powerful treatments, including cell- and gene-based therapies with multi-million-dollar price tags, the need for sensible drug pricing policies will only intensify. The Right ...
In a unique collaboration, The Breast Cancer Fund, the American Cancer Society, and the Susan G. Komen Breast Cancer Foundation invited artists and writers across the nation who had faced breast cancer to submit their work. The result is Art.Rage.Us., a riveting book of art, fiction, poetry, and prose, and a bold testimony to the courage of women who face the disease. At turns stirring, humorous, heartrending, introspective, stark, and defiant, the pieces in Art.Rage.Us. have the power to comfort, provoke, and transform. For each of the 75 artists, the impulse to transform her experience of breast cancer through creative expression was an integral part of the search for healing. Together their work forms a inspiring statement about the healing power of art.
'A lively study of the Big C, which makes the case that cancer is the price we pay for our marvellously complicated bodies.' The Times, best books of 2020 'This book is packed with big ideas about life. Every chapter has something in it which made me think wow. Having worked in a major cancer charity for many years, Arney writes with genuine in-depth understanding and is a perfect guide.' Daniel M. Davis, author of The Beautiful Cure 'Rebel Cell is a bright, engaging read, fizzing with energy and metaphor. Kat Arney is a science writer for all of us - a powerful and talented story teller.' Stephen McGann 'Kat's book is Dynamite. A crystal clear reappraisal of the story behind that word we fe...
Climate change is a complex phenomenon with a wide range of impacts on the environment. Biotic and abiotic stress are a result of climate change. Abiotic stress is caused by primary and secondary stresses which are an impediment to plant productivity. Prolonged exposure to these stresses results in altered metabolism and damage to biomolecules. Plants evolve defense mechanisms to withstand these stresses, e.g. synthesis of osmolytes, osmoprotectants, and antioxidants. Stress responsive genes and gene products including expressed proteins are implicated in conferring tolerance to the plant. This volume will provide the reader with a wide spectrum of information, including vital references. It...
Indian Political Thought: Themes and Thinkers covers all major Indian political thinkers from the ancient, through medieval to the modern times. Thus, this book provides an overview of the evolution of the Indian political thought through different historical periods, giving an insight into the sociological and political conditions of the times that shaped the Indian political thinking. It does not only talk about the lives and times of the thinkers, but also explores the important themes that formed the basis of their political ideologies. The chapters discuss the contributions of the thinkers and at the same time examine some important themes including the theory of state, civil rights, ideal polity, governance, nationalism, democracy, social issues like gender and caste, swaraj, satyagraha, liberalism, constitutionalism, Marxism, socialism and Gandhism. With a comprehensive coverage of both the thinkers and the themes of the Indian political thought, this book caters to needs of the undergraduate as well as the post graduate courses of all Indian universities. It is valuable also for UGC-NET and civil service examinations.