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In Vivo Immunology
The 11th International Conference on Lymphoid Tissues and Immune Reactions was held in Spa-Liege (Belgium), from 4 to 8 July 1993. The regular devotees refer to these conferences as the "Germinal Centre Conferences or GCC". In the 1960s, the germinal centres were the subject of such considerable study and speculation that a group of dynamic people decided to devote an international conference centered on that topic. This led to the fIrst GCC organized in Bern in 1966. Following the success of this initial meeting, further sessions have been organized at regular intervals and, over the years, the scope of the GCC has been broadened. Nowadays, the GCC conferences are dedicated to in vivo immun...
Stress and Immunity
Stress and Immunity introduces and updates the status of research on stress and immunity. Clinical aspects of stress and immunity are presented in the first 17 chapters and include discussions regarding the influence of depression disorders on immune functions and stress interrelationships with cancer, AIDS, Chronic Fatigue Syndrome, and Herpes Simplex infections. There is also a review of physical exercise and immunity. The second half of the book is devoted to discussions regarding basic research being conducted in the field of stress and immunity. This includes discussions on the interrelationships of the central nervous system and the immune system and research on stress hormones (e.g., enkephalins, endorphins) as they interrelate with the immune system. In addition, animal models for the study of stress and immunity are discussed. Psychiatrists, neurologists, psychologists, clinical psychologists, internists, immunologists, and researchers in psychosomatic disorders should consider this an essential reference volume.
Progress in Virus Research
The first part of the book deals with several aspects of different viruses : viral structure, function, replication and interplay between the virus and the host. Six viruses are used as examples, four RNA viruses (HTLV-I, HIV-1, MMTV and coxsackievirus B4) and two DNA viruses (EBV and KSHV). The second part of the book is devoted to the use of the knowledge on viruses to practical applications and also to the characterisation of HIV inhibitors. Reviewing the results of research on different viruses is important since, although viruses possess vast degrees of complexity, they also share similar features. In addition, viruses are more and more used as models to solve molecular biology problems.
Immune Tolerance Research Developments
Immune or immunological tolerance is the process by which the immune system does not attack an antigen. It occurs in three forms: central tolerance, peripheral tolerance and acquired tolerance. Central tolerance is immunological tolerance developed during T and B cell differentiation. Peripheral tolerance is immunological tolerance developed after T and B cells mature and enter the periphery. Acquired or induced tolerance is the immune system's tolerance for external antigens. This book presents the latest research from around the world.
Neuroendocrine and Neural Regulation of Autoimmune and Inflammatory Disease
Neuroendocrine immunology is a growing branch of medicine. The 28 papers in this volume are taken from the 5th Congress of the International Society for NeuroImmunoModulation, held in France in 2002, and relate to the neuroimmunomodulation of the autoimmune diseases.
Neuroscience Year
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The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance
The focus of this eBook is to bring new insights into central immune tolerance. To fulfill that, much has been discussed about the master in the regulation of tolerance, the autoimmune regulator (Aire) gene the main thymus cell type that expresses this gene, the medullary thymic epithelial cells (mTECs). It includes one Editorial and 12 other excellent contributions in the format of mini reviews or original research papers covering one or more of these aspects: promiscuous gene expression (PGE), epigenetics, miRNAs, association of the Aire gene and miRNAs, thymocyte–TEC interaction, coxsackievirus and type 1 diabetes, exosomes in the thymus, thymic crosstalk, thymic B cells, T cell develop...
Regulatory Peptides in Neuroscience and Endocrinology: A New Era Begins
This Research Topic features recent developments in the field of regulatory peptide physiology and peptide-based therapeutics.
Neuroendocrine Perspectives
Topics of special interest in current research are presented in each volume of the series Neuroendocrine Perspectives. Volume 8 has five major sections that address new findings in our knowledge of the CNS neurotransmitter and neuropeptide systems. They broaden the traditional view of the hypothalamo-pituitary control and of the modulation of brain function by target hormones.
Thymus Transcriptome and Cell Biology
This volume focuses on challenging field in biomedicine that is the genetic control of central immune tolerance. It covers the thymus development, their cellular components and their respective function, the peculiar gene expression profiling (transcriptome) found in the medullary thymic epithelial cells (mTECs) that are implicated in the self-representation in the thymus, the Autoimmune regulator (Aire) gene, the mutations in this gene and manifestation of autoimmune diseases, and the role of cell-cell interactions within the thymus with implications in the negative selection (elimination) of nascent autoreactive T cells in preventing aggressive autoimmunity. The thymus gland is a lymphoid organ implicated in the maturation, differentiation and selection of T cells. This organ is gained more and more attention in different biomedical research labs worldwide due to its function that is associated with the control of immune homeostasis in the body, establishing the central immune tolerance and preventing the onset of autoimmune diseases.
