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Visions of Freedom: Havana, Washington, Pretoria, and the Struggle for Southern Africa, 1976-1991
This book compiles recent research on the modification of nucleic acids. It covers backbone modifications and conjugation of lipids, peptides and proteins to oligonucleotides and their therapeutic use. Synthesis and application in biomedicine and nanotechnology of aptamers, fluorescent and xeno nucleic acids, DNA repair and artificial DNA are discussed as well.
When Will, Earl of Rastleigh meets Helena Swift, he is intrigued by her composure, her kindness and her intelligence. As their friendship develops, he realises he has found his ideal wife, if only he can slip past her guard and overcome her well-known aversion to matrimony. Tempted by the thought of children of her own, and encouraged by her mother to leave the shallows where she has lingered since her fiancé died of the wounds he received at Waterloo, Helena accepts Will's offer of a marriage based not on dangerous love but affectionate companionship and mutual respect. But is this enough? As Will gets to know his wife better, and the secrets of her past unfold, he realises that they have settled for second-best. Can he change the basis of their marriage? Will Helena risk her heart and dare to love again?
Coverage has been extended to include recent topics. The book again presents a unified treatment of economic theory, with the method of maximum likelihood playing a key role in both estimation and testing. Exercises are included and the book is suitable as a general text for final-year undergraduate and postgraduate students.
This volume details protocols on rationale design of therapeutic siRNA molecules and its encapsulation with smart vehicles to overcome the barriers to an effective administration in vivo. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Design and Delivery of SiRNA Therapeutics aims to ensure successful results in the further study of this vital field. This volume details protocols on rationale design of therapeutic ...
Este libro surge del espíritu inquieto de los estudiantes y profesores del curso Seminario de Evaluación de la Teoría para la Práctica y la Investigación, del doctorado en Enfermería de la Facultad de Enfermería de la Universidad Nacional de Colombia. Trasciende de la lectura comprensiva a la materialización del pensamiento complejo para demostrar desde la práctica de enfermería los enlaces filosóficos, conceptuales y teóricos en la solución de necesidades del cuidado de la salud de las personas. En cada uno de los capítulos se presentan, por medio de una narrativa, las interacciones entre el/la enfermero/a y el sujeto de cuidado, los cambios ocurridos entre esta díada y la argumentación de los diferentes enlaces soportados en el conocimiento construido por la enfermería.
This book collects the publications of the special Topic Scientific advances in STEM: from Professor to students. The aim is to contribute to the advancement of the Science and Engineering fields and their impact on the industrial sector, which requires a multidisciplinary approach. University generates and transmits knowledge to serve society. Social demands continuously evolve, mainly because of cultural, scientific, and technological development. Researchers must contextualize the subjects they investigate to their application to the local industry and community organizations, frequently using a multidisciplinary point of view, to enhance the progress in a wide variety of fields (aeronaut...