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This indispensable volume highlights recent studies identifying epigenetic mechanisms as essential regulators of skin development, stem cell activity and regeneration. Chapters are contributed by leading experts and promote the skin as an accessible model system for studying mechanisms that control organ development and regeneration. The timely discussions contained throughout are of broad relevance to other areas of biology and medicine and can help inform the development of novel therapeutics for skin disorders as well as new approaches to skin regeneration that target the epigenome. Part of the highly successful Stem Cells and Regenerative Medicine series, Epigenetic Regulation of Skin Development and Regeneration uncovers the fundamental significance of epigenetic mechanisms in skin development and regeneration, and emphasizes the development of new therapies for a number of skin disorders, such as pathological conditions of epidermal differentiation, pigmentation and carcinogenesis. At least six categories of researchers will find this book essential, including stem cell, developmental, hair follicle or molecular biologists, and gerontologists or clinical dermatologists.
This book, written by experts from across the world, provides comprehensive coverage of acne and rosacea, focusing in particular on pathogenesis and treatment but also considering clinical aspects, prognostic factors, and impacts on quality of life. Both standard knowledge and important, clinically relevant insights that have emerged over the past decade are presented with the goal of assisting the reader in understanding these diseases and improving treatment outcome. It is explained how high-level research has recently given rise to a variety of new concepts in etiology and treatment, and emerging trends are also discussed. The book is in a reader-friendly format that highlights core messages with a very practical and clinical focus. Pathogenesis and Treatment of Acne and Rosacea will be an indispensable reference for all physicians who care for patients with acne or rosacea and for scientists working in the field.
Hair disorders have become a central social and psychological issue and patients now have increasing demands and expectations. Written by world-renowned experts, this lavishly illustrated book provides the latest scientific aspects of hair biology, up to date knowledge on hair diagnosis and treatment options as well as hair removal and restoration techniques. The content is divided into three sections: basic aspects of hair growth; hair and scalp disorders; and fotoepilation, surgery and hair cosmetics. In addition, coverage is enhanced with unique sections on hair in different ages and in art, on ethnic hair and in forensic investigations.
This volume explores the possible functional significance of proopiomelanocortin-derived peptides and their receptor expression in human skin. It particularly focuses on the modulation of skin immune and stress responses, and in the pathogenesis of several important skin diseases with a recognized neuroimmunologic component, such as atopic eczema, contact allergy, uticaria, and psoriasis.
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This book addresses the importance of the physicians’ understanding on how varying ethnic and cultural identities can affect dermatological disease presentation in patients. It bridges the gap in knowledge for practicing dermatologists, especially those not studying or practicing in a highly multi-ethnic center who may not be exposed to patients from a variety of cultures. Concise and cohesive, the book examines how dermatoses can manifest due to cosmetic practices, therapeutics, religious practices, cultural hair-related practices, and environmental variables. These elements underscore that without exposure to patients of varying backgrounds, it can be nearly impossible to learn about pra...
The landmark dermatology text that bridges the gap between science and clinical medicine. Covers all aspects of skin diseases and diseases of other organs that involve the skin.