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Advances in Virus Research
Advances in Virus Research
Ruminant Pestivirus Infections
Findings concerning various clinical manifestations in cattle and sheep have made it clear that pestivirus infections in ruminants have an economic impact similar to hog cholera. Early data justified the classification of pestiviruses as a genus of nonarthopod-borne togaviruses. Since pestiviruses are difficult to work with, progress in understanding the virus and disease gradually came to a standstill because conventional techniques failed to yield further insights. About ten years ago interest in pestivirology was revived by strong impulses of modern biotechnology and a breakthrough in pathogenesis research, i.e. in vitro translation of BVD viral proteins and the ex experimental reproduction of mucosal disease in cattle. In order to summarize and discuss these exciting developments, an international community of pestivirus researchers came together in June 1990 in Hannover (Federal Republic of Germany) for the Symposium "Ruminant Pestivirus Infections: Virology, Pathogenesis and Perspectives on Prophylaxis". This book is a selection of papers presented at this symposium.
Infectious Diseases of Wild Mammals and Birds in Europe
INFECTIOUS DISEASES OF WILD MAMMALS AND BIRDS IN EUROPE Infectious Diseases of Wild Mammals and Birds in Europe is a key resource on the diagnosis and treatment of infectious diseases in European wildlife that covers the distinctive nature of diseases as they occur in Europe, including strains, insect vectors, reservoir species, and climate, as well as geographical distribution of the diseases and European regulations for reporting, diagnosis and control. Divided into sections on viral infections, bacterial infections, fungal and yeast infections, and prion infections, this definitive reference provides valuable information on disease classification and properties, causative agents, epidemio...
Frontiers in Clinical Drug Research: Anti-Infectives
Frontiers in Clinical Drug Research – Anti Infectives is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti Infectives is...
100 Years of Virology
One hundred years ago, when Martinus W. Beijerinck in Delft and Friedrich Loeffler on Riems Island discovered a new class of infectious agents in plants and animals, a new discipline was born. This book, a compilation of papers written by well-recognized scientists, gives an impression of the early days, the pioneer period and the current state of virology. Recent developments and future perspectives of this discipline are sketched against a historic background. With contributions by A. Alcami, D. Baulcombe, F. Brown, L. W. Enquist, H. Feldmann, A. Garcia-Sastre, D. Griffiths, M. C. Horzinek, A. van Kammen, H.-D. Klenk, F. A. Murphy, T. Muster, R. O'Neill, P. Palese, C. Patience, R. Rott, H.- P. Schmiedebach, S. Schneider-Schaulies, G. L. Smith, J. A. Symons, Y. Takeuchi, V. ter Meulen, P. J. W. Venables, V. E. Volchkov, V. A. Volchkova, R. A. Weiss, W. Wittmann, H. Zheng.
Control of Pestivirus Infections in the Management of Wildlife Populations
Infections with recognized and putative species of the genus pestivirus are not host-specific and are documented in many wildlife species. The study of pestivirus infections in wildlife species is important both to eradication programs and programs for maintaining the health and well-being of wildlife populations. Free-ranging wildlife species may act as reservoirs for pestiviruses that infect domestic species. For this reason, eradication efforts for classical swine fever virus include control of the virus in wild boar populations. The contribution of free-ranging species to the circulation of BVDV1, BVDV2, and BDV is less well understood. While substantial damage due to pestivirus infections has been demonstrated in a few specific wildlife populations, the impact of pestiviral infections on the well-being of most captive and free-ranging wildlife populations is largely unknown. The research topics summarizes our current understanding of pestiviral infections in wildlife and discusses the challenges in understanding and mediating their impact on captive and free ranging wildlife species.
Epidemiology and Control of Notifiable Animal Diseases
Surveillance, early detection, control and eradication of notifiable animal diseases is of critical importance for countries in order to maintain or improve their animal health status. This requires the collaboration of all stakeholders involved including animal health authorities, livestock industry and veterinary research institutions among others. Prevention, control and eradication programs must take into account the characteristics of the host (including potential reservoirs), the pathogen (transmissibility, virulence…) and the environment (temperature, animal density…) but also the socio-economic context in which they have to be implemented (highly influenced by funding availabilit...
Vaccines and Diagnostics for Transboundary Animal Diseases
Transboundary animal diseases (TADs) are a major threat to livestock. They are highly contagious or transmissible, and they have the potential to cause high morbidity and mortality in both susceptible animal populations and humans. In addition, not only are TADs detrimental to national economies, they are also a serious threat to world food security. This volume presents the proceedings of an international workshop on Vaccines and Diagnostics for Transboundary Animal Diseases that was held in Ames (Iowa, USA) in 2012. Experts and scientists from academia, industry and government reviewed the current status of vaccines and diagnostics for high priority TADs, decision-making and regulatory processes for veterinary biologics, and the roles and responsibilities of government agencies. The discussions also addressed achievements and gaps in vaccine and diagnostics development for 11 important TADs as well as the translation of research findings into licensed novel vaccines and diagnostics for high-priority TADs.
