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Organelle-Specific Pharmaceutical Nanotechnology
This book introduces and discusses the latest in biomedical research--Pharmaceutical Nanotechnology applied at the sub-cellular level.
Multifunctional Pharmaceutical Nanocarriers
The editors have brought together leading experts in multifunctional nanopharmaceuticals to provide cutting edge information; a critical overview of the field; and analysis of current and potential future developments to speed the subject’s rapid development.
Liposome Technology, Second Edition
Liposome Technology, Second Edition, is an updated, expanded new edition of a classic volume in the field. It covers all aspects of liposome technology, including liposome preparation and analysis, drug entrapment, and techniques used for in vivo and in vitro evaluation of liposomes. Leading authorities have contributed 70 chapters to create what is destined to be the standard liposome technology book for the 1990s. Many of the chapters describe methodologies practiced in authors' laboratories and provide specific examples of how these methodologies are applied in specific circumstances. Liposome Technology, Second Edition will be an essential reference volume for academic and industrial researchers in pharmacology, pharmacy, medicine, biochemistry, and immunology. What's new in the 2nd Edition? The 2nd Edition covers significant developments in liposome technology that have occurred since the publication of the 1st Edition in 1982. These developments include the following: New preparative procedures Special approaches to accommodate the incorporation of certain drugs New targeting techniques Large scale production of liposomes, patents, and clinical trials
Synthetic DNA Delivery Systems
DNA delivery into cells is a rapidly developing area in gene therapy and biotechnology. Moreover, it is a powerful research tool to determine gene structure, regulation, and function. Viral methods of DNA delivery are well-characterized and efficient, but little is known about the toxicity and immunogenecity of viral vectors. As a result, non-viral, transfection methods of DNA delivery are of increasing interest. Synthetic DNA Delivery Systems is a comprehensive and current resource on DNA transfection. The use of histidine-rich peptides and polypeptides as DNA delivery systems and self-assembled delivery systems based on cationic lipids and polymers are discussed. Targeted delivery to organelles, tumor cells and dendritic cells comprise an important topic.
Nanoparticulates as Drug Carriers
Written by key experts in the field of nanomedicine, this book provides a broad introduction to the important field of nanomedicine and application of nanotechnology for drug delivery. It covers up-to-date information regarding various nanoparticulate drug delivery systems, describes the various opportunities for the application of nanoparticular drug carriers in different areas of clinical medicine, and analyzes already available information on their clinical applications.This book can be used as an advanced textbook by graduate students and young scientists and clinicians at the early stages of their career. It is also suitable for non-experts from related areas of chemistry, biochemistry,...
Biomedical Aspects of Drug Targeting
Drugs usually have no natural affinity for the cells, tissues and organs where therapeutic effects are needed, which frequently results in low efficiency and unwanted side effects. This concern is even more profound when using highly potent and cytotoxic anticancer drugs or specific agents, such as enzymes and genetic materials, since their effective and safe action requires precise cellular or even sub-cellular addressing in the target organ. To meet safety, efficiency and specificity requirements, drugs somehow must be targeted to the sites of their expected therapeutic action. The idea of the "magic bullet," or drug targeting, proposed by Erlich a century ago, generates great and continuo...
Liposome Technology
Liposome Technology, Volume II: Entrapment of Drugs and Other Materials into Liposomes, Third Edition is a comprehensively updated and expanded new edition of a classic text in the field. Including step-by-step technical details, Volume II describes procedures for the incorporation of drugs and other materials into liposomes for a variety therapeut
Nanomedicine
This volume comprehensively covers cancer, cardiovascular and the central nervous system of nanomedicine. With an international board of authors, this volume is split into sections that cover subjects such as diabetes and nanotechnology as potential therapy, and nanomedicines for inflammatory diseases.
Liposomes
This third edition provides new and updated chapters detailing preparation of liposomes, physicochemical characterization of liposomes, lipid analysis, drug encapsulation, surface modification, stimuli response as well as cellular interaction, and biodistribution. Also included is an updated chapter on the history and evolution of the field of liposomology. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Liposomes: Methods and Protocols, Third Edition aims to serve as a reference for graduate students, post-doctoral researchers as well as established investigators utilizing lipid-based systems.
