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Viral Infections of Humans
This latest edition of the classic text includes new and greatly revised chapters on laboratory methods in epidemiology, human herpesvirus types 6 and 7, parvovirus, and retroviruses. The book covers the principles and approaches to the study of viral infections in human populations, major virus classes of medical and public health importance, and neoplastic and other slowly developing diseases due to viral infection.
The Herpesviruses
The first volume of the nineteen-volume series entitled Comprehensive Virology was published in 1974 and the last is yet to appear. We noted in 1974 that virology as a discipline had passed through its descriptive and phenomenological phases and was joining the molecular biology rev olution. The volumes published to date were meant to serve as an in depth analysis and standard reference of the evolving field of virology. We felt that viruses as biological entities had to be considered in the context of the broader fields of molecular and cellular biology. In fact, we felt then, and feel even more strongly now, that viruses, being simpler biological models, could serve as valuable probes for ...
The Herpesviruses
The Herpesviruses provides information pertinent to all the herpesviruses, with emphasis on the classification, morphology, replication, physical–chemical properties, and immunological relationships of all the herpesviruses. This book presents the fundamental and clinical aspects of the viruses. Organized into 21 chapters, this book starts with an overview of the classification of the herpesvirus and proceeds to explore the origins and phylogeny of the herpesviruses. This text then examines the earliest electron microscopic studies on the morphology of the herpesviruses by using shadowcast preparations of herpes simplex virus and of herpes zoster virus. Other chapters consider the serological tests as well as the antigenic relationships among herpesviruses. The final chapter deals with the clinical application of antiviral drug treatment. This book is a valuable resource for virologists, molecular biologists, veterinarians, physicians, as well as teachers and graduate students who are interested in the herpesviruses from either a fundamental or clinical viewpoint.
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Infections Causing Human Cancer
Infections must be thought as one of the most important, if not the most important, risk factors for cancer development in humans. Approximately 15-20% of all cases of cancer around the world are caused by viruses. The establishment of a causal relationship between the presence of specific infective agents and certain types of human cancer represents a key step in the development of novel therapeutic and preventive strategies. In this book, Professor zur Hausen (Nobel Prize in Physiology/Medicine 2008) provides a thorough and comprehensive overview on carcinogenic infective agents -- viruses, bacteria, parasites and protozoons -- as well as their corresponding transforming capacities and mechanisms. The result is an invaluable and instructive reference for all oncologists, microbiologists and molecular biologists working in the area of infections and cancer. The author was among the first scientists to reveal the cervical cancer-inducing mechanisms of human papilloma viruses and isolated HPV16 and HPV18, and, as early as 1976, published the hypothesis that wart viruses play a role in the development of this type of cancer.
The Epstein-Barr Virus
The Epstein-Barr virus was discovered 15 years ago. Since that time an immense body of information has been accumu lated on this agent which has come to assume great signifi cance in many different fields of biological science. Thus, the virus has very special relevance in human medicine and oncology, in tumor virology, in immunology, and in mole cular virology, since it is the cause of infectious mononu cleosis and also the first human cancer virus, etiologically related to endemic Burkitt's lymphoma and probably to nasopharyngeal carcinoma. In addition, continuous human lymphoid cell lines initiated and maintained by the transform ing function of the virus genome provide a laboratory tool ...
Advances in Cancer Research
Advances in Cancer Research
Advances in Immunology
Advances in Immunology
