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This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.
Dieses Fachbuch erläutert die molekularen Grundlagen von Entzündungen, spannt den Bogen zu Infektionskrankheiten und den Zusammenhang zwischen Entzündungen und chronischen Erkrankungen, behandelt abschließend den Heilungsprozess und zeigt Therapiemöglichkeiten.
Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summ...
Sepsis is a serious condition that is associated with high mortality despite advanced modern medical treatment. Recent years have witnessed novel paradigms describing host responses in sepsis. In particular, the delicate balance between pro- and anti-inflammatory reactions has been subject to intense research. This volume in the book series ‘Contributions to Microbiology’ presents the state of the art in this rapidly expanding field of research. Leading international experts have contributed with reviews on the most relevant topics in the field such as clinical aspects, pathways of sepsis and pro- and anti-inflammatory mechanisms as well as their regulation. The book will be a valuable source of up-to-date information for clinicians, microbiologists, immunologists, and students with an interest in the complex regulation of host responses during microbial sepsis.
Offering a global, multidisciplinary perspective on this life-threatening medical emergency, The Sepsis Codex provides a concise yet comprehensive look at a complex topic. Nearly 20% of global deaths are attributed to sepsis annually, nearly half of which are in children under the age of five, with low-resource settings being disproportionately affected. A "one size fits all approach is not sufficient to meet individual patients' needs, instead requiring a therapeutic approach that considers different ages, predisposing factors, genetic traits, and more. This cutting-edge resource brings you up to date with recent medical advances in this challenging area. - Covers pathophysiology, early detection, biomarkers and diagnosis, therapies, controversies, future research, the use of AI, professional organizations and public health in sepsis. - Includes chapters on sepsis in special populations such as in pregnant women, transplanted patients, and children. - Consolidates today's available information on this timely topic into a single, convenient resource.
Using an easily accessible, highly templated format, Clinical Cases in Tropical Medicine, 2nd Edition, provides more than 100 realistic scenarios for tropical infectious diseases. Full-color photographs and maps, a convenient question-and-answer presentation, and succinct summary boxes help you identify and understand the tropical diseases you’re likely to encounter. This up-to-date 2nd Edition is an excellent resource and study tool for infectious diseases fellows, doctors preparing for exams in tropical medicine, primary care doctors with patients who are global travelers, and global health nurses and practitioners alike. Offers realistic scenarios for encountering patients in rural, res...
Confidently meet the demands of transitioning students into practice-ready nurses with Medical-Surgical Nursing: Focus on Clinical Judgment, 3rd Edition. Expertly curated by experienced clinician and nursing educator Dr. Linda Honan, this practical approach distills complex concepts down to need-to-know details through the perspective of practicing nurses, establishing a comprehensive foundation in medical-surgical nursing by way of the most commonly encountered conditions and situations. Extensive updates throughout this 3rd Edition broaden your students’ perspectives, cultivate their clinical judgment, and prepare them for success from the Next Generation NCLEX® to the day-to-day challenges of today’s medical-surgical nursing practice.
"The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals" is an indispensable resource for physicians, nurse practitioners, physician assistants, pharmacists, and nurses in managing critically ill patients. This comprehensive guide delves deep into the world of vasopressors and inotropes, offering a blend of scientific understanding using evidence-based medicine and practical wisdom. Authored by Dr. Eddy J Gutierrez, a board-certified Intensivist, this handbook begins with the basic pillars of hemodynamics. It then progresses beyond basic concepts to detailed discussions on each type of vasopressor and inotrope, providing insights into their clinical applications,...
Features, Transmission, Detection, and Case Studies in COVID-19 examines the effects of the virus on the body, as well as its transmission and clinical profile. This volume begins with an introduction to the virus and its pathogenesis, transmission, and avoidance, followed by sections on pulmonary and cardiovascular effects, obesity, diabetes, the liver, detection issues, and biomarkers. Vaccines and treatment are also discussed. Specific case studies covered include hypoxia, acute kidney injury, pneumonia, and neurological effects. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19. - Discusses COVID-19 biology, including...
The conditions and characteristics of correctional facilities - overcrowded with rapid population turnover, often in old and poorly ventilated structures, a spatially concentrated pattern of releases and admissions in low-income communities of color, and a health care system that is siloed from community public health - accelerates transmission of the novel coronavirus (SARS-CoV-2) responsible for COVID-19. Such conditions increase the risk of coming into contact with the virus for incarcerated people, correctional staff, and their families and communities. Relative to the general public, moreover, incarcerated individuals have a higher prevalence of chronic health conditions such as asthma,...