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Drug Transport Across the Blood-brain Barrier
The availability of various in vitro and in vivo techniques has considerably advanced the research on drug transport and metabolism across the blood-brain barrier (BBB). These specialized and sophisticated experimental strategies are of fundamental importance if one is to gain a greater understanding of enhanced and selective drug delivery to the brain. The reader will find in this book methods for in vitro endothelial/astrocyte cell culture models, and for in vivo intracerebral microdialysis to study drug tranport across the BBB. This book, however, is not merely a laboratory manual consisting of recipes for BBB research; it permits the presentation of the different methods in fine detail, ...
Sustainability in Biofuel Production Technology
Sustainability in Biofuel Production Technology Explore current challenges and the latest technologies in biofuel production In Sustainability in Biofuel Production Technology, a team of engineers and chemists delivers a thorough and accessible exploration of the source of renewable energy biofuels poised to help conserve natural resources and limit the impact of fossil fuel use. The book offers detailed information about the challenges and trends in biodiesel production and includes contributions from leading researchers in the field of biodiesel production. Readers will explore aviation biofuels, biofuel production technologies, reactor design and safety considerations, and the modelling a...
Focus on Cerebral Palsy Research
Cerebral palsy is an umbrella-like term used to describe a group of chronic disorders impairing control of movement that appear in the first few years of life and generally do not worsen over time. The disorders are caused by faulty development of or damage to motor areas in the brain that disrupts the brain's ability to control movement and posture. Symptoms of cerebral palsy include difficulty with fine motor tasks, difficulty maintaining balance or walking, involuntary movements. The symptoms differ from person to person and may change over time. Some people with cerebral palsy are also affected by other medical disorders, including seizures or mental impairment, but cerebral palsy does not always cause profound handicap. Early signs of cerebral palsy usually appear before 3 years of age. Infants with cerebral palsy are frequently slow to reach developmental milestones such as learning to roll over, sit, crawl, smile, or walk. Cerebral palsy may be congenital or acquired after birth. There is no standard therapy that works for all patients. This new book gathers outstanding new research and insights from throughout the world.
The Memory System of the Brain
The purpose of this book is to describe the memory system of the brain, taking into account all the levels of neural organization: molecule, cell, small network, and anatomical circuit. This synthetic approach is necessary for determining the real mechanisms among the potential ones, that is the neural bases of learning and memory in intact organisms functioning under normal conditions. For this purpose, data from molecular, cellular and behavioral neurobiology, neuropsychology, animal and human psychology, and neural modellization are comprehensively reviewed by leading specialists and brought together in an original synthesis.
Drugs of Abuse, Immunity, and AIDS
This volume is based on the program of the Second International Conference on Drugs of Abuse, Immunity and AIDS, held in Clearwater Beach, FL in June 1992. The Conference was supported in part by the University of South Florida College of MediCine with financial assistance from the National Institute on Drug Abuse. The focus of this conference was the effects of drugs of abuse on immunity. It is now widely recognized that psychoactive drugs of abuse, including marijuana, cocaine, and opiates, as well as alcohol, have marked effects in an individual, including effects on their nervous system and behavior. In the past two decades, the scope of studies concerning the effects of some drugs of ab...
Handbook of Powder Science & Technology
Since the publication of the first edition of Canada, and Australia have increased teach Handbook of Powder Science and Technology, ing, research, and training activities in areas the field of powder science and technology has related to particle science and technology. gained broader recognition and its various ar In addition, it is worth mentioning the many eas of interest have become more defined and books and monographs that have been pub focused. Research and application activities lished on specific areas of particle, powder, related to particle technology have increased and particle fluid by professional publishers, globally in academia, industry, and research technical societies and university presses. Also, institutions. During the last decade, many to date, there are many career development groups, with various scientific, technical, and courses given by specialists and universities on engineering backgrounds have been founded various facets of powder science and technol to study, apply, and promote interest in areas ogy.
Handbook of Theories of Aging, Second Edition
The field of gerontology has often been criticized for being "data-rich but theory-poor." The editors of this book address this issue by stressing the importance of theory in gerontology. While the previous edition focused on multidisciplinary approaches to aging theory, this new edition provides cross-disciplinary, integrative explanations of aging theory: The contributors of this text have reached beyond traditional disciplinary boundaries to partner with researchers in adjacent fields in studying aging and age-related phenomena. This edition of the Handbook consists of 39 chapters written by 67 internationally recognized experts in the field of aging. It is organized in seven sections, re...
Spouted and Spout-Fluid Beds
Since the pioneering text by Mathur and Epstein over 35 years ago, much of the work on this subject has been extended or superseded, producing an enormous body of scattered literature. This edited volume unifies the subject, pulling material together and underpinning it with fundamental theory to produce the only complete, up-to-date reference on all major areas of spouted bed research and practice. With contributions from internationally renowned research groups, this book guides the reader through new developments, insights and models. The hydrodynamic and reactor models of spouted and spout-fluid beds are examined, as well as such topics as particle segregation, heat and mass transfer, mixing and scale-up. Later chapters focus on drying, particle-coating and energy-related applications based on spouted and spout-fluid beds. This is a valuable resource for chemical and mechanical engineers in research and industry.
Biochemical Basis of Functional Neuroteratology
Biochemical Basis of Functional Neuroteratology
Biology of Aging
Robert Arking's Biology of Aging, 3rd edition, is an introductory text to the biology of aging which gives advanced undergraduate and graduate students a thorough review of the entire field. His prior two editions have also served admirably as a reference text for clinicians and scientists. This new edition captures the extraordinary recent advances in our knowledge of the ultimate and proximal mechanisms underlying the phenomenon of aging. As a result, six important conceptual changes are included here: · Clarified distinctions between the biological mechanisms involved in longevity determination and those involved in senescent processes. · A new conceptual framework around which we can o...
