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Published Scientific Papers of the National Institutes of Health
Each issue lists papers published during the preceding year.
Psychopharmacology and Aging
This volume represents the proceedings of a Symposium on Psychopharmacology and the Aging Patient, held at Duke University, May 29-31, 1972. The conference was jointly sponsored by the Center for the Study of Aging and Human Development and the Department of Psychiatry at Duke. This Symposium was the first in a series of conferences which will be devoted variously to preclinical and clinical pharmacology of the different groups of psychotropic drugs, especially as they relate to the problems of the elderly patient and to the special considerations that must be given in theory and in practice to changes brought about by the process of aging. The idea behind this particular symposium was to br...
Current Trends in Lithium and Rubidium Therapy
Lithium research and therapy needs to be continually re-evaluated on the basis of modern methodological approaches in order to shed new light on the mechanism of action and to improve therapeutic use. This book. based on the proceedings of the "International Meeting on Lithium and Rubidium Therapy" held in Venice from September 30th to October 2nd 1983. is devoted to current trends in the pharmacology and clinical aspects of lithium and of a newly born therapeutic cation. rubidium. The first part of this volume deals with modern trends in behavioural and biochemical approaches to the mechanism of action of lithium. A larger consideration is reserved for lithium therapy from a clinical point ...
Models of Depressive Disorders
This volume is the second in a series on depressive illness. The first volume, entitled Phenomenology of Depressive Illness, is de voted to a description of depressive illness from many vantage points including that of the patient as well as the psychiatrist. Epidemiological, nosological, and developmental aspects are included together with specific descriptions of major subtypes of depressive illness. It is only after an illness is fully described that an attempt should be made to generate models with ex planatory and predictive properties. This second volume is that next step. The major models of depressive illness are described. The limited progress that has been made in integrating these...
Psychotic Continuum
One of the most important questions of our previous common volumes about affective, schizoaffective, and schizophrenic disorders was the question of what connects and what separates psychotic disorders (Marneros and Tsuang, Schizo affective Psychoses, Springer-Verlag, 1986; Marneros and Tsuang Affective and Schizoaffective Disorders, Springer-Verlag, 1990; Marneros, Andreasen, and Tsuang, Negative and Positive Schizophrenia, Springer-Verlag 1993). The boundaries between various psychotic disorders are not always clearly defined. Some groups of psychotic disorders, such as schizoaffective disorders and all the other "atypical" psychoses, occupy a position between "typical" mental disorders, s...
Manic-Depressive Illness
The revolution in psychiatry that began in earnest in the 1960s led to dramatic advances in the understanding and treatment of manic-depressive illness. Hailed as the most outstanding book in the biomedical sciences when it was originally published in 1990, Manic-Depressive Illness was the first to survey this massive body of evidence comprehensively and to assess its meaning for both clinician and scientist. It also vividly portrayed the experience of manic-depressive illness from the perspective of patients, their doctors, and researchers. Encompassing an understanding about the illness as Kraeplin conceived of it- about its cyclical course and about the essential unity of its bipolar and ...
Pathological Neurochemistry
More than for any other volume of the Handbook of Neurochemistry, the chap ters in this volume on Pathological Neurochemistry deal with the interface of the laboratory bench with the patient's bedside. Most of the chapters reflect the confluence of basic scientists, clinical investigators, and physicians. Con sidered here are many of the more important disorders that afflict the nerves, muscles, spinal cord, and/or brain of mankind throughout the world. There are well over 500 such disorders. And our understanding of their nature and of measures for effective prevention or treatment depends significantly on appli cation of the biochemical disciplines that characterize neurochemistry. Before ...
