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An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version
This volume provides a comprehensive overview of the hazards inherent in herbal medicinal products, with systematic coverage of major toxicities. Topics include composition and quality control, toxicokinetics, interactions, safety pharmacology, approaches to studying complex mixtures including metabolomics and systems network pharmacology, and long-term toxicity. The volume also discusses various organ toxicities with a special emphasis on basic mechanisms of actions and the multicomponent and multi-target nature of herbal products. It concludes with a look to future challenges and opportunities. With contributions from noted experts, Toxicology of Herbal Products is a necessary resource for physicians, pharmacists, and toxicologists interested in complex plant-derived products.
Reviews of Environmental Contamination and Toxicology provides concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.
Featuring the improved format used in the 5th edition, this updated set presents, in logical groupings, comprehensive toxicological data for industrial compounds, including CAS numbers, physical and chemical properties, exposure limits, and biological tolerance values for occupational exposures, making it essential for toxicologists and industrial hygienists. This edition has about 40% new authors who have brought a new and international perspective to interpreting industrial toxicology, and discusses new subjects such as nanotechnology, flavorings and the food industry, reactive chemical control to comprehensive chemical policy, metalworking fluids, and pharmaceuticals.
This book covers varied aspects of environmental contaminants and their effect on the living organisms. It addresses the basics of ecotoxicity assessment, interaction of the abiotic or biotic factors with the novel chemical entities, and the fate of the natural organic matter upon interaction with new chemical entities. It further includes models for ecotoxicity studies and high-throughput approaches including OMICS. It provides an overview of the ecological risk assessment, regulatory toxicology guidelines, and possible roadmaps for protection of environmental health. Features: Discusses environmental toxicology facets and their effects on the ecosystem. Provides an introduction of environmental toxicology keeping in view the paradigm shift on entry of novel materials in the environment. Includes bioavailability, bioconcentration, and biomagnification of trophic transfer of pollutants. Covers high-throughput approaches for ecotoxicity assessment. Explores roadmaps for environmental protection and sustainable development. This book is geared toward graduate students and researchers in Environmental Sciences and Engineering, Toxicology, and Ecology.
Environmental Toxicology provides a detailed, comprehensive introduction to this key area of sustainability and public health research. The broad coverage includes sections on ecological risk assessment, monitoring, mechanisms, fate and transport, prevention, and correctives, as well as treatment of the health effects of solar radiation and toxicology in the ocean. The 23 state-of-the-art chapters provide a multi-disciplinary perspective on this vital area, which encompasses environmental science, biology, chemistry, and public health.
Providing a concise, yet comprehensive, reference on all aspects of industrial exposures and toxicants; this book aids toxicologists, industrial hygienists, and occupational physicians to investigate workplace health problems. • Updates and expands coverage with new chapters covering regulatory toxicology, toxicity testing, physical hazards, high production volume (HPV) chemicals, and workplace drug use • Includes information on occupational and environmental sources of exposure, mammalian toxicology, industrial hygiene, medical management and ecotoxicology • Retains a succinct chapter format that has become the hallmark for the previous editions • Distils a vast amount of information into one resource for both academics and professionals
Microextraction Techniques in Analytical Toxicology provides the information readers need to include about cutting-edge sample preparation techniques into their everyday analytical practice, including comprehensive information about principles and state-of-the-art microextraction sample preparation techniques for the analysis of drugs and poisons in biological specimens, especially in forensic and clinical settings. This book also focuses on theoretical discussions of solid-based and liquid-based microextraction techniques, their method development, validation, and applications. A detailed compilation of analytical protocols based on published microextraction procedures to aid in method deve...