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Anti-tuberculosis Drug Resistance in the World
Multidrug-resistant tuberculosis (MDR-TB) has been recorded at the highest rates ever, according to this new report that presents findings from the largest survey to date on the scale of drug resistance in tuberculosis. This fourth global report is based on information collected between 2002 and 2006 on 90,000 TB patients in 81 countries. It also found that extensively drug-resistant tuberculosis (XDR-TB), a virtually untreatable form of the respiratory disease, has been recorded in 45 countries. The primary aim of this report is to share survey and surveillance data on drug resistance in TB. The data presented here are supplied largely by the program managers who have led the work on surveys, but also heads of reference laboratories as well as principle investigators that may have been hired to assist the national Tuberculosis Program with the study.
Anti-tuberculosis Drug Resistance in the World
This is the third report of the WHO/IUATLD project which gives comparable worldwide information on anti-tuberculosis drug resistance, with data from surveys conducted in 77 different countries or geographical settings during the years 1999 to 2002. Global surveillance identifies areas of high resistance and draws the attention of national authorities to address the problems involved. The report also highlights the importance of conducting surveillance on re-treatment cases, and the role of the laboratory in TB control.
Guidelines for the Programmatic Management of Drug-resistant Tuberculosis
The emergence of extensively drug-resistant strains of tuberculosis, especially in countries with a high prevalence of human immunodeficiency virus, is a serious threat to global public health and jeopardizes efforts to effectively control the disease. This publication offers updated recommendations for the diagnosis and management of drug-resistant tuberculosis in a variety of geographical, economic and social settings, and the recording of data that enables the monitoring and evaluation of programs.--Publisher's description.
Tuberculosis, Leprosy and Mycobacterial Diseases of Man and Animals
Mycobacteria are bacterial pathogens which cause diseases in humans and non-human animals. This monograph will primarily cover the most important and widely researched groups of mycobacteria: members of the Mycobacterium tuberculosis complex (MTC) and Mycobacterium leprae, across a wide range of host species. M. tuberculosis and M. bovis are particularly relevant with the increasing drug resistance and co-infection with HIV associated with M. tuberculosis and the possible cross-infection of badgers and cattle associated with M. bovis. This book will provide a reference for researchers working in different fields creating a work which draws together information on different pathogens, and by considering the diseases in a zoonotic context provides a One Health approach to these important groups of diseases.
HIV & TB Drug Resistance & Clinical Management Case Book
This book is an excellent practical compendium of knowledge in the field of HIV and TB drug resistance that will be of immense use to clinicians, nurses, and other caregivers. It provides expert guidance as to what to do in difficult clinical situations and what steps should be taken to prevent the emergence and transmission of drug resistance
Assessing Tuberculosis Prevalence Through Population-based Surveys
This publication provides countries with practical guidelines for planning population-based surveys to estimate the prevalence of tuberculosis (TB) at a national level. TB prevalence surveys yield useful information in areas where notification data obtained through routine surveillance are incomplete, or of unproven accuracy, and in areas with an estimated TB prevalence of more than 100 per 100 000. These surveys are used to evaluate the performance of the TB program, and to assess trends over time. To achieve this objective, data are collected through standards methods in a well-defined study population. This document is meant to provide information on the core survey methods, including diagnostic tests for TB, screening strategies, and case definitions. The target audience includes TB experts and advisers at national and international levels, and investigators involved in prevalence surveys.
Multidrug Resistance: A Global Concern
Multiple drug resistance among bacteria has become a global issue with a considerable impact on the mortality associated with infectious diseases. This book is a detailed compilation of available knowledge on the surveillance and mechanisms of antibiotic resistance in various countries throughout the world. Readers will be updated on current information on the understanding of mechanisms involved in drug resistance and the geographical distribution of resistance determinant markers. This volume should be a useful guide for microbiologists and clinicians interested in designing antimicrobial therapies tailored for patients in specific geographical regions.
Tuberculosis
Every second a new person is exposed to tuberculosis (TB). Each untreated TB-infected person will infect 10-15 people every year. Following the success of its predecessor, this new edition of Tuberculosis: The Essentials scrutinizes the new discoveries and observations of the key aspects of the disease. Recognized world experts provide a concise, state-of-the-art review of the 15 essential elements of TBsupply an international, current view of the epidemiology, pathophysiology, diagnosis, and treatment methodsdiscuss the emerging threat of XDR-TB and the HIV/AIDS factorassess advances in TB research such as new drugs and vaccinesreflect on the progress of the "Stop TB" strategy.
