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Practical Management of Hypertension
WILLEM H. BIRKENHA. GER This compact guide aims to define the current approach to hypertension in practice, with the focus on the individual whom the physician faces across his desk. In the population, blood pressures are distributed along a Gaussian type of curve, but with some tailing towards the upper range. A systolic blood pressure of 160 mmHg is commonly accepted as the upper limit of the normal range. For diastolic pressure, the gradings are much more detailed: borderline hypertension (90-94 mmHg, mild hypertension (95-104 mmHg), moderate hypertension (105-114 mmHg), and severe hypertension (115 mmHg and over). Despite its skewing to the right, the bell shape of the distribution curve...
Frontiers in Hypertension Research
reached full definition in the 1940s by Kempner diet. The important role of adrenal aldosterone and associates in demonstrating the beneficial ef secretion in supporting human hypertension is now fects of a low salt rice diet for treating hypertensive well recognized as are the beneficial effects of patients. It became apparent that the value of rice blockade, especially in low-renin patients who ex was wholly related to its sodium content. A rice hibit inappropriate or absolute excesses of aldoste diet, or any other stringent low sodium diet, rone secretion. Further definition of the more sub greatly improves or completely corrects the hyper tle participation of aldosterone and of the facto...
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Research Progress in Alzheimer's Disease and Dementia
Alzheimer's disease (AD), the most common form of neurodegenerative disorder in the elderly, is characterised pathologically by extracellular amyloid plaques and intracellular neurofibrillary tangles, pathophysiologically by synaptic dysfunction, and clinically by a progressive decline in cognition. Currently, AD has no cure and its prevalence is predicted to triple by 2050 with the rapid increase in the ageing population, unless more effective treatments are developed. Since the publication of the second book volume, the rapid progress in the research fields of AD and dementia continues through the intensive efforts of research scientists worldwide. This third book volume contains 15 chapte...
Pharmacology of Antihypertensive Drugs
Handbook of Hypertension, Volume 3: Pharmacology of Antihypertensive Drugs presents the biological and clinical knowledge in the field of hypertension. This book discusses the fundamental pharmacology of antihypertensive drugs. Organized into 12 chapters, this volume begins with an overview of the classification of antihypertensive mechanisms of drugs. This text then examines the effects of antihypertensive drugs in animal models and discusses the importance of these models and responses to human hypertension. Other chapters consider the pharmacological basis for the treatment of hypertension. This book discusses as well the various classes of antihypertensive drugs, which depends on two factors. The final chapter deals with the inhibitors of angiotensin-converting enzyme, which are essential in the drug treatment of hypertensive disease. This book is a valuable resource for clinicians, pharmacists, physiologists, epidemiologists, biological scientists, and general practitioners. Clinical investigators and medical students will also find this book extremely useful.
Genetics of Hypertension
Classic and modern tools of genetics have been applied to hypertension research for some 20 years. This volume in the Handbook of Hypertension series aims to go beyond a simple summary of discoveries and provides a critical commentary on many controversial issues. It will be particularly useful for clinician scientists at all stages of their careers, graduate students and post-doctoral scientists as well as all those interested in cardiovascular medicine and research throughout the entire spectrum from bench to bedside. As in every relatively young area of research, the initial excitement over the early positive observations has not always been confirmed by subsequent larger studies with gre...
Manual of Nonpharmacological Control of Hypertension
The prevention and correction of high blood pressure obviously is not an end in itself but a means of preventing cardiovascular complications. It is tempting to res ort to antihypertensive drugs, for the simple reason that current preparations are easy to dose and to take. There is a variety of reasons, however, to take advantage of the antihypertensive potential of nonpharmaco logical approaches first. For one thing, the use of tablets tends to accentuate the negative effects oflabelling a subject as hypertensive. The act oftaking tablets per se may elicit a spectrum of subjective adverse effects, as we have learned from placebo-controlled therapeutic trials. Even more importantly, the bene...
Hypertension in the Twentieth Century
This unique volume records and interprets the revolutionary advances made in the understanding of hypertension during the twentieth century and provides pointers to the future. Many of the contributing authors are prominent participants in the major discoveries related to hypertension. This volume also draws together the different strands in the development of the subject: the scientific and clinical; the North American and European; the technological and the epidemiological. A particular focus is the clinical trial. The editors have encouraged controversial views especially in the criticism directed towards the limitations of meta-analysis, the defects (and virtues) of the currently fashionable large clinical trials, and the sporadic disingenuous interpretation of some trials. This volume of the Handbook of Hypertension series also serves to bring together the key contents and concepts presented in the previous twenty-one volumes. It will set a firm foundation for future volumes that will together continue to provide a major reference work on this important health problem.
