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From the time of its establishment in the eighteenth century until late in the nineteenth century, the University of Pennsylvania's School of Medicine was the most respected medical institution in the United States. Today it is among the leaders in medical education in the U.S. It continues to play a crucial role in the development of medical education, the practice of medicine, and medical research in America. Innovation and Tradition at the University of Pennsylvania School of Medicine: An Anecdotal Journey presents a thoroughly researched, readable history of this important institution. Tracing its growth from a couple of courses at the College of Philadelphia to its 225th anniversary in 1990, the authors highlight the truly remarkable contributions to science and medicine made by members of the school's distinguished faculty. including Benjamin Rush, Caspar Wistar, Joseph Leidy, Simon Flexner, lsador Ravdin, and Britton Chance.
The story told in this book begins in about 1700, when the first attempts were made to study the diseased heart in life (the subject matter of cardiology), as distinct from its appearance after death; it ends, rather arbitrarily, in 1970. The account of the development of knowledge of heart disease is mainly chronological with emphasis on the fruitful consequences of the cross-fertilization of clinical practice with pathological anatomy at the beginning of the nineteenth century and with physiology at the end. In addition, shorter chapters deals with such topics as specific disease entities, methods of investigation, cardiac surgery and the work of two individuals - Peter Latham, an example of a physician practising with today's clinical skills but a very imperfect knowledge of the pathogenesis of heart disease and Etienne Marey, an early exponent of the clinical physiology which would, in time, throw light on that pathogenesis.
The field of pediatric cardiology was in its early stages of development when the author of this book began his career in the mid-1960s, meaning that he was able to witness the stepwise evolution of the field over the last 50 years. This book presents this unique historical perspective, describing the development of new knowledge while providing care of patients with heart disease over this time period. It brings together advances made in the field, particularly regarding the management of congenital heart defects.
The main aim of this monograph is to provide an overview of calcium regulation in cardiac muscle cells, particularly with respect to excitation-contraction coupling and the control of cardiac contractile force. It is my hope that this book will be useful to students of the cardiovascular system and muscle at all different levels and in different disciplines (such as physiology, biochemistry, pharmacology and pathophysiology). I also hope that it will find use for those studying developmental, comparative and disease processes as well as more integrative phenomenon. I kept several goals in mind in writing this monograph. First, it should be easily readable. Second, I chose to include numerous...
primary goal of all forms of therapy is not just prolonging life, but improving the quality of life, has forced analysis of what constitutes quality of life, a concept whose structure pervades all walks of life and eludes definition. Global well being, happiness, morale, vitality, fullness of social life, and satisfaction must be integrated and assessed for the effects of the disease and the therapy, in the context of specific personality traits, attitudes to life, family situation, and socio-economic and political freedom. A growing inter est in research on this subject has led to a clearer understanding of the components which come to determine quality of a patient's life, and how they can...
For almost 40 years, a small but intense group of cardiovascular investigators have evaluated cardiac performance by measuring the mass, velocity, and acceleration of blood ejected from the left ventricle. These studies reveal that energy is transferred from ventricle to blood very early in systole, and that the left ventricle is charac terized as an impulse generator. Recent explosive developments in Doppler echocar diography have allowed study of the energetics of ventricular contraction through noninvasive acceleration, velocity, and volumetric flow measurements. Compared against reference standards of ejection fraction, dP/dt, and instantaneous pressure gradient across the aortic valve, ...
CARDIAC VALVE ALLOGRAFTS (HOMOGRAFTS) highlights the current controversy about freehand subcoronary aortic valve and root replacement with regard to postoperative morbidity and long term durability. It discusses particular implantation techniques of preference in young patients and in different root pathology. Other chapters address intermediate- and long-term results on cardiac valve and vascular homografts for treating complicating cardiac valve and aortic infections. The chapter on basic science additionally makes this book a highly authoritative reference source for cardiac surgeons, physicians and scientists. This work provides a current survey of the state-of-the-art.
February issue includes Appendix entitled Directory of United States Government periodicals and subscription publications; September issue includes List of depository libraries; June and December issues include semiannual index
Europace '97 was held in Athens, Greece, on 8-11 June Leads were, as usual, an important topic, with the earl 1997 in the city of classical civilisation and learning. iest mention of the then-new polyurethane leads. Future Though now held in modem surroundings and meeting conferences elaborated on these basic topics while pro facilities, the influence of the ancient city-state was un gressively adding sensors and sensor function, dual mistakable, with the architecture and learning of antiquity chamber pacing, and recognising the development of looming over the city, by its influence over the intellectual clinical cardiac electrophysiology. activities of the symposium. The ancient magnificenc...